Actinobacillus pleuropneumoniae Osteomyelitis in Pigs Demonstrated by Fluorescent in Situ Hybridization
Research output: Contribution to journal › Journal article › Research › peer-review
Necrotizing osteomyelitis and fibrinopurulent arthritis with isolation of Actinobacillus pleuropneumoniae serotype 2 is reported in two pigs from a herd with lameness and mild coughing problems among 8 to 12-week-old pigs. Application of fluorescent in situ hybridization targeting 16S ribosomal RNA of A. pleuropneumoniae in formalin-fixed tissue was performed to verify the association of A. pleuropneumoniae with the bone and joint lesions. By in situ hybridization A. pleuropneumoniae was demonstrated as multiple microcolonies or single cells dispersed in focal fibrinonecrotizing pleuropneumonia, in joints with arthritis, and in bone necroses including lysis of growth plate and suppurative inflammation in the adjacent trabecular metaphysis, thus demonstrating that well-known infections manifest new, unusual lesions.
Original language | English |
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Journal | Veterinary Pathology |
Volume | 36 |
Issue number | 3 |
Pages (from-to) | 258-261 |
Number of pages | 4 |
ISSN | 0300-9858 |
DOIs | |
Publication status | Published - May 1999 |
Externally published | Yes |
- Actinobacillus pleuropneumoniae, Arthritis, In situ hybridization, Osteomyelitis, Pigs
Research areas
ID: 339895833