A role for the weak DnaA binding sites in bacterial replication origins

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A role for the weak DnaA binding sites in bacterial replication origins. / Charbon, Godefroid; Løbner-Olesen, Anders.

In: Molecular Microbiology, Vol. 82, No. 2, 2011, p. 272-274.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Charbon, G & Løbner-Olesen, A 2011, 'A role for the weak DnaA binding sites in bacterial replication origins', Molecular Microbiology, vol. 82, no. 2, pp. 272-274. https://doi.org/10.1111/j.1365-2958.2011.07840.x

APA

Charbon, G., & Løbner-Olesen, A. (2011). A role for the weak DnaA binding sites in bacterial replication origins. Molecular Microbiology, 82(2), 272-274. https://doi.org/10.1111/j.1365-2958.2011.07840.x

Vancouver

Charbon G, Løbner-Olesen A. A role for the weak DnaA binding sites in bacterial replication origins. Molecular Microbiology. 2011;82(2):272-274. https://doi.org/10.1111/j.1365-2958.2011.07840.x

Author

Charbon, Godefroid ; Løbner-Olesen, Anders. / A role for the weak DnaA binding sites in bacterial replication origins. In: Molecular Microbiology. 2011 ; Vol. 82, No. 2. pp. 272-274.

Bibtex

@article{d485fa44890747d28b5a8995b19dfb14,
title = "A role for the weak DnaA binding sites in bacterial replication origins",
abstract = "DnaA initiates the chromosomal DNA replication in nearly all bacteria, and replication origins are characterized by binding sites for the DnaA protein (DnaA-boxes) along with an 'AT-rich' region. However, great variation in number, spatial organization and specificity of DnaA-boxes is observed between species. In the study by Taylor et al. (2011), new and unexpectedly weak DnaA-boxes were identified within the Caulobacter crescentus origin of replication (Cori). The position of weak and stronger DnaA-boxes follows a pattern seen in Escherichia coli oriC. This raises the possibility that bacterial origins might be more alike than previously thought.",
keywords = "Bacterial Proteins/chemistry, Binding Sites, Caulobacter crescentus/chemistry, Chromosomes, Bacterial/genetics, DNA Replication, DNA-Binding Proteins/chemistry, Protein Binding, Replication Origin",
author = "Godefroid Charbon and Anders L{\o}bner-Olesen",
note = "{\textcopyright} 2011 Blackwell Publishing Ltd.",
year = "2011",
doi = "10.1111/j.1365-2958.2011.07840.x",
language = "English",
volume = "82",
pages = "272--274",
journal = "Molecular Microbiology",
issn = "0950-382X",
publisher = "Wiley-Blackwell",
number = "2",

}

RIS

TY - JOUR

T1 - A role for the weak DnaA binding sites in bacterial replication origins

AU - Charbon, Godefroid

AU - Løbner-Olesen, Anders

N1 - © 2011 Blackwell Publishing Ltd.

PY - 2011

Y1 - 2011

N2 - DnaA initiates the chromosomal DNA replication in nearly all bacteria, and replication origins are characterized by binding sites for the DnaA protein (DnaA-boxes) along with an 'AT-rich' region. However, great variation in number, spatial organization and specificity of DnaA-boxes is observed between species. In the study by Taylor et al. (2011), new and unexpectedly weak DnaA-boxes were identified within the Caulobacter crescentus origin of replication (Cori). The position of weak and stronger DnaA-boxes follows a pattern seen in Escherichia coli oriC. This raises the possibility that bacterial origins might be more alike than previously thought.

AB - DnaA initiates the chromosomal DNA replication in nearly all bacteria, and replication origins are characterized by binding sites for the DnaA protein (DnaA-boxes) along with an 'AT-rich' region. However, great variation in number, spatial organization and specificity of DnaA-boxes is observed between species. In the study by Taylor et al. (2011), new and unexpectedly weak DnaA-boxes were identified within the Caulobacter crescentus origin of replication (Cori). The position of weak and stronger DnaA-boxes follows a pattern seen in Escherichia coli oriC. This raises the possibility that bacterial origins might be more alike than previously thought.

KW - Bacterial Proteins/chemistry

KW - Binding Sites

KW - Caulobacter crescentus/chemistry

KW - Chromosomes, Bacterial/genetics

KW - DNA Replication

KW - DNA-Binding Proteins/chemistry

KW - Protein Binding

KW - Replication Origin

U2 - 10.1111/j.1365-2958.2011.07840.x

DO - 10.1111/j.1365-2958.2011.07840.x

M3 - Journal article

C2 - 21958322

VL - 82

SP - 272

EP - 274

JO - Molecular Microbiology

JF - Molecular Microbiology

SN - 0950-382X

IS - 2

ER -

ID: 200971366