Phenotypic Characterization and Comparative Genomic Analysis of Novel Salmonella Bacteriophages Isolated from a Tropical Rainforest
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Salmonella infections across the globe are becoming more challenging to control due to the emergence of multidrug-resistant (MDR) strains. Lytic phages may be suitable alternatives for treating these multidrug-resistant Salmonella infections. Most Salmonella phages to date were collected from human-impacted environments. To further explore the Salmonella phage space, and to potentially identify phages with novel characteristics, we characterized Salmonella-specific phages isolated from the Penang National Park, a conserved rainforest. Four phages with a broad lytic spectrum (kills >5 Salmonella serovars) were further characterized; they have isometric heads and cone-shaped tails, and genomes of similar to 39,900 bp, encoding 49 CDSs. As the genomes share a
Originalsprog | Engelsk |
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Artikelnummer | 3678 |
Tidsskrift | International Journal of Molecular Sciences |
Vol/bind | 24 |
Udgave nummer | 4 |
Antal sider | 15 |
ISSN | 1661-6596 |
DOI | |
Status | Udgivet - 2023 |
ID: 339326118