NMR-based metabolomics for identification of α-amylase inhibitors in rowan berries (Sorbus spp.)
Publikation: Konferencebidrag › Poster › Forskning
Dokumenter
- Danish NMR meeting 2015 SISO
Indsendt manuskript, 15,6 MB, PDF-dokument
Type 2 diabetes is a metabolic disorder estimated to affect millions of people all over the world.1 One way of reducing diabetes-related complications is to control
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
postprandial glucose.2 Inhibition of the carbohydrate digestive enzyme α-amylase is a therapeutic target for maintaining low blood glucose levels. A study from 2011
shows that berries from Sorbus spp (rowan berries) effectively inhibit α-amylase activity and suggests that the active compounds are proanthocyanidins.3 The aim of this
project is to identify the rowan berry species with highest α-amylase inhibitory activity - and to find a 1H-NMR method suitable for NMR-based metabolomics
Originalsprog | Engelsk |
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Publikationsdato | 2015 |
Antal sider | 1 |
Status | Udgivet - 2015 |
Begivenhed | 36th Danish NMR Meeting - Lund, Sverige Varighed: 19 jan. 2015 → 20 jan. 2015 |
Konference
Konference | 36th Danish NMR Meeting |
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Land | Sverige |
By | Lund |
Periode | 19/01/2015 → 20/01/2015 |
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