Transcript elongation by RNA polymerase II

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Standard

Transcript elongation by RNA polymerase II. / Selth, Luke A.; Sigurdsson, Stefan; Svejstrup, Jesper Q.

I: Annual Review of Biochemistry, Bind 79, 07.07.2010, s. 271-293.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Selth, LA, Sigurdsson, S & Svejstrup, JQ 2010, 'Transcript elongation by RNA polymerase II', Annual Review of Biochemistry, bind 79, s. 271-293. https://doi.org/10.1146/annurev.biochem.78.062807.091425

APA

Selth, L. A., Sigurdsson, S., & Svejstrup, J. Q. (2010). Transcript elongation by RNA polymerase II. Annual Review of Biochemistry, 79, 271-293. https://doi.org/10.1146/annurev.biochem.78.062807.091425

Vancouver

Selth LA, Sigurdsson S, Svejstrup JQ. Transcript elongation by RNA polymerase II. Annual Review of Biochemistry. 2010 jul. 7;79:271-293. https://doi.org/10.1146/annurev.biochem.78.062807.091425

Author

Selth, Luke A. ; Sigurdsson, Stefan ; Svejstrup, Jesper Q. / Transcript elongation by RNA polymerase II. I: Annual Review of Biochemistry. 2010 ; Bind 79. s. 271-293.

Bibtex

@article{c951e6ad720e4e57a9b4455d94df72f4,
title = "Transcript elongation by RNA polymerase II",
abstract = "Until recently, it was generally assumed that essentially all regulation of transcription takes place via regions adjacent to the coding region of a gene-namely promoters and enhancers-and that, after recruitment to the promoter, the polymerase simply behaves like a machine, quickly reading the gene. However, over the past decade a revolution in this thinking has occurred, culminating in the idea that transcript elongation is extremely complex and highly regulated and, moreover, that this process significantly affects both the organization and integrity of the genome. This review addresses basic aspects of transcript elongation by RNA polymerase II (RNAPII) and how it relates to other DNA-related processes.",
keywords = "chromatin, elongation factors, gene traffic, transcription-associated recombination, transcription-repair coupling",
author = "Selth, {Luke A.} and Stefan Sigurdsson and Svejstrup, {Jesper Q.}",
year = "2010",
month = jul,
day = "7",
doi = "10.1146/annurev.biochem.78.062807.091425",
language = "English",
volume = "79",
pages = "271--293",
journal = "Annual Review of Biochemistry",
issn = "0066-4154",
publisher = "Annual Reviews, inc.",

}

RIS

TY - JOUR

T1 - Transcript elongation by RNA polymerase II

AU - Selth, Luke A.

AU - Sigurdsson, Stefan

AU - Svejstrup, Jesper Q.

PY - 2010/7/7

Y1 - 2010/7/7

N2 - Until recently, it was generally assumed that essentially all regulation of transcription takes place via regions adjacent to the coding region of a gene-namely promoters and enhancers-and that, after recruitment to the promoter, the polymerase simply behaves like a machine, quickly reading the gene. However, over the past decade a revolution in this thinking has occurred, culminating in the idea that transcript elongation is extremely complex and highly regulated and, moreover, that this process significantly affects both the organization and integrity of the genome. This review addresses basic aspects of transcript elongation by RNA polymerase II (RNAPII) and how it relates to other DNA-related processes.

AB - Until recently, it was generally assumed that essentially all regulation of transcription takes place via regions adjacent to the coding region of a gene-namely promoters and enhancers-and that, after recruitment to the promoter, the polymerase simply behaves like a machine, quickly reading the gene. However, over the past decade a revolution in this thinking has occurred, culminating in the idea that transcript elongation is extremely complex and highly regulated and, moreover, that this process significantly affects both the organization and integrity of the genome. This review addresses basic aspects of transcript elongation by RNA polymerase II (RNAPII) and how it relates to other DNA-related processes.

KW - chromatin

KW - elongation factors

KW - gene traffic

KW - transcription-associated recombination

KW - transcription-repair coupling

U2 - 10.1146/annurev.biochem.78.062807.091425

DO - 10.1146/annurev.biochem.78.062807.091425

M3 - Review

C2 - 20367031

AN - SCOPUS:77953629213

VL - 79

SP - 271

EP - 293

JO - Annual Review of Biochemistry

JF - Annual Review of Biochemistry

SN - 0066-4154

ER -

ID: 330899430