Transcatheter Mitral Valve Repair or Replacement: Competitive or Complementary?

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  • Zhang Xiling
  • Thomas Puehler
  • Søndergaard, Lars
  • Derk Frank
  • Hatim Seoudy
  • Baland Mohammad
  • Oliver J. Müller
  • Stephanie Sellers
  • David Meier
  • Janarthanan Sathananthan
  • Georg Lutter

Over the last two decades, transcatheter devices have been developed to repair or replace diseased mitral valves (MV). Transcatheter mitral valve repair (TMVr) devices have been proven to be efficient and safe, but many anatomical structures are not compatible with these technologies. The most significant advantage of transcatheter mitral valve replacement (TMVR) over transcatheter repair is the greater and more reliable reduction in mitral regurgitation. However, there are also potential disadvantages. This review introduces the newest TMVr and TMVR devices and presents clinical trial data to identify current challenges and directions for future research.

OriginalsprogEngelsk
Artikelnummer3377
TidsskriftJournal of Clinical Medicine
Vol/bind11
Udgave nummer12
ISSN2077-0383
DOI
StatusUdgivet - 2022

Bibliografisk note

Funding Information:
Funding: We are very grateful receiving financial support from the DZHK (German Center for cardiovascular research); Grant 11/2022.

Funding Information:
Conflicts of Interest: T.P. is a consultant for Abbott. G.L. is a consultant for Edwards Lifesciences and Abbott. D.F. is a consultant for Edwards Lifesciences and Medtronic and has received research funding from Edwards Lifesciences. M.S. is a consultant for Medtronic. J.S. is a consultant for Edwards Lifesciences, Boston Scientific and Medtronic and received speaker fees from Edwards. He has also received institutional research funds from Edwards Lifesciences and Medtronic. L.S. has received consultant fees and/or institutional research grants from Abbott, Boston Scientific, Medtronic, and SMT. D.M. is supported by the Swiss National Science Foundation (grant P2LAP3_199561). L.S. has received consultant fees and/or institutional research grants from Abbott, Boston Scientific, Medtronic and SMT All other authors have no commercial or financial relationships that could be construed as potential conflicts of interest.

Publisher Copyright:
© 2022 by the authors. Licensee MDPI, Basel, Switzerland.

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