Tooth Loss and Chronic Pain: A Population-based Analysis of the National Health and Nutrition Examination Survey
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Tooth Loss and Chronic Pain : A Population-based Analysis of the National Health and Nutrition Examination Survey. / Ma, Kevin Sheng Kai; Chan, Shu Yen; Van Dyke, Thomas E.; Wang, Shiow Ing; Wei, James Cheng Chung; Ashina, Sait.
I: Journal of Pain, 2024.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Tooth Loss and Chronic Pain
T2 - A Population-based Analysis of the National Health and Nutrition Examination Survey
AU - Ma, Kevin Sheng Kai
AU - Chan, Shu Yen
AU - Van Dyke, Thomas E.
AU - Wang, Shiow Ing
AU - Wei, James Cheng Chung
AU - Ashina, Sait
N1 - Publisher Copyright: © 2024 United States Association for the Study of Pain, Inc.
PY - 2024
Y1 - 2024
N2 - Poor oral health conditions in adults are associated with chronic pain. A nationwide cross-sectional study was conducted to investigate the link between tooth loss and chronic pain. The study involved 8,662 participants from the National Health and Nutrition Examination Survey. Tooth count was categorized into 4 groups, and chronic pain was defined as persistent pain lasting over 3 months despite treatment. Location of the chronic pain, demographics, comorbidities, lifestyle determinants, and dietary intake were retrieved. Univariate and multivariate logistic regression were used to explore cross-sectional associations between tooth count and chronic pain. Compared to participants with more than 20 teeth, those with severe tooth loss presented greater odds of chronic pain (adjusted odds ratio [aOR] = 2.111, 95% confidence intervals (CI) = 1.213–3.676 for patients with 1–8 teeth). Edentulous participants presented with significantly higher odds of chronic pain in the lower extremities (78.4%) and buttocks (49.5%). In the multivariate model, apart from rheumatic arthritis (aOR = 4.004, 95% CI = 2.766–5.798), variables of higher chronic pain included smoking (aOR = 1.518, 95% CI = 1.228–1.878), and hypertension (aOR = 1.463, 95% CI = 1.013–2.112). On the contrary, being Mexican American (aOR = .603, 95% CI = .414–.880) was associated with lower odds of chronic pain. The findings suggested a significant link between chronic pain and tooth loss, independent of ethnicity, lifestyle determinants, and immune-mediated inflammatory diseases including rheumatoid arthritis. Perspective: A U.S. nationwide study examined tooth loss and chronic pain. Those with severe tooth loss had increased odds of chronic pain. Edentulous individuals presented higher odds of pain in lower extremities and buttocks. This study highlighted the link between tooth loss and chronic pain, independent of comorbidities and lifestyle factors.
AB - Poor oral health conditions in adults are associated with chronic pain. A nationwide cross-sectional study was conducted to investigate the link between tooth loss and chronic pain. The study involved 8,662 participants from the National Health and Nutrition Examination Survey. Tooth count was categorized into 4 groups, and chronic pain was defined as persistent pain lasting over 3 months despite treatment. Location of the chronic pain, demographics, comorbidities, lifestyle determinants, and dietary intake were retrieved. Univariate and multivariate logistic regression were used to explore cross-sectional associations between tooth count and chronic pain. Compared to participants with more than 20 teeth, those with severe tooth loss presented greater odds of chronic pain (adjusted odds ratio [aOR] = 2.111, 95% confidence intervals (CI) = 1.213–3.676 for patients with 1–8 teeth). Edentulous participants presented with significantly higher odds of chronic pain in the lower extremities (78.4%) and buttocks (49.5%). In the multivariate model, apart from rheumatic arthritis (aOR = 4.004, 95% CI = 2.766–5.798), variables of higher chronic pain included smoking (aOR = 1.518, 95% CI = 1.228–1.878), and hypertension (aOR = 1.463, 95% CI = 1.013–2.112). On the contrary, being Mexican American (aOR = .603, 95% CI = .414–.880) was associated with lower odds of chronic pain. The findings suggested a significant link between chronic pain and tooth loss, independent of ethnicity, lifestyle determinants, and immune-mediated inflammatory diseases including rheumatoid arthritis. Perspective: A U.S. nationwide study examined tooth loss and chronic pain. Those with severe tooth loss had increased odds of chronic pain. Edentulous individuals presented higher odds of pain in lower extremities and buttocks. This study highlighted the link between tooth loss and chronic pain, independent of comorbidities and lifestyle factors.
KW - Chronic pain
KW - Inflammation
KW - Nutrition deficiency
KW - Periodontitis
KW - Tooth loss
U2 - 10.1016/j.jpain.2024.104529
DO - 10.1016/j.jpain.2024.104529
M3 - Journal article
C2 - 38588761
AN - SCOPUS:85193602918
JO - The Journal of Pain
JF - The Journal of Pain
SN - 1526-5900
M1 - 104529
ER -
ID: 393054878