The Signature Biobank: A longitudinal biopsychosocial repository of psychiatric emergency patients
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The Signature Biobank : A longitudinal biopsychosocial repository of psychiatric emergency patients. / Kerr, Philippe; Le Page, Cécile; Giguère, Charles Édouard; Marin, Marie France; Trudel-Fitzgerald, Claudia; Romain, Ahmed Jérôme; Taschereau-Dumouchel, Vincent; Ouellet-Morin, Isabelle; Lecomte, Tania; Potvin, Stéphane; Geoffrion, Steve; Sasseville, Marc; Caihol, Lionel; Lipp, Olivier; Pelletier, Jean François; Dumais, Alexandre; Lesage, Alain; Labelle, Réal; Lavoie, Marc; Godbout, Roger; Vincent, Philippe; Boissonneault, Janick; Findlay, Helen; Lupien, Sonia J.; Guay, Stéphane; Juster, Robert Paul; Consortium, Signature.
I: Psychiatry Research, Bind 332, 115718, 02.2024.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The Signature Biobank
T2 - A longitudinal biopsychosocial repository of psychiatric emergency patients
AU - Kerr, Philippe
AU - Le Page, Cécile
AU - Giguère, Charles Édouard
AU - Marin, Marie France
AU - Trudel-Fitzgerald, Claudia
AU - Romain, Ahmed Jérôme
AU - Taschereau-Dumouchel, Vincent
AU - Ouellet-Morin, Isabelle
AU - Lecomte, Tania
AU - Potvin, Stéphane
AU - Geoffrion, Steve
AU - Sasseville, Marc
AU - Caihol, Lionel
AU - Lipp, Olivier
AU - Pelletier, Jean François
AU - Dumais, Alexandre
AU - Lesage, Alain
AU - Labelle, Réal
AU - Lavoie, Marc
AU - Godbout, Roger
AU - Vincent, Philippe
AU - Boissonneault, Janick
AU - Findlay, Helen
AU - Lupien, Sonia J.
AU - Guay, Stéphane
AU - Juster, Robert Paul
AU - Consortium, Signature
N1 - Publisher Copyright: © 2024 Elsevier B.V.
PY - 2024/2
Y1 - 2024/2
N2 - The Signature Biobank is a longitudinal repository of biospecimen, psychological, sociodemographic, and diagnostic data that was created in 2012. The Signature Consortium represents a group of approximately one hundred Quebec-based transdisciplinary clinicians and research scientists with various expertise in the field of psychiatry. The objective of the Signature Biobank is to investigate the multi-faceted underpinnings of psychiatric disorders among patients in crisis. The Signature Consortium is expanding and includes new active members that seek to highlight the contributions made by Signature Biobank since its inception. This article details our research protocol, directions, and summarizes contributions. To date, we have collected biological samples (n = 1,986), and questionnaire data (n = 2,085) from psychiatric emergency patients of the Institut universitaire en santé mentale de Montréal (Quebec, Canada), with a large proportion from whom both data types were collected (n = 1,926). In addition to this, a subsample of patients was followed-up at hospital discharge, and two additional outpatient clinic appointments (n = 958 with at least one follow-up). In addition, a socio-demographically matched comparison group of individuals who were not hospitalized for psychiatric disorders (n = 149) was recruited from the surrounding catchment area. To summarize, a systematic review of the literature shows that the Signature Biobank has contributed to better characterizing psychiatric comorbidities, biological profiles, and psychosocial functioning across some of the most common psychiatric disorders, including psychosis, mood, anxiety, and substance use disorders. The Signature Biobank is now one of the world's largest repositories of data collected from patients receiving care at a psychiatric emergency unit.
AB - The Signature Biobank is a longitudinal repository of biospecimen, psychological, sociodemographic, and diagnostic data that was created in 2012. The Signature Consortium represents a group of approximately one hundred Quebec-based transdisciplinary clinicians and research scientists with various expertise in the field of psychiatry. The objective of the Signature Biobank is to investigate the multi-faceted underpinnings of psychiatric disorders among patients in crisis. The Signature Consortium is expanding and includes new active members that seek to highlight the contributions made by Signature Biobank since its inception. This article details our research protocol, directions, and summarizes contributions. To date, we have collected biological samples (n = 1,986), and questionnaire data (n = 2,085) from psychiatric emergency patients of the Institut universitaire en santé mentale de Montréal (Quebec, Canada), with a large proportion from whom both data types were collected (n = 1,926). In addition to this, a subsample of patients was followed-up at hospital discharge, and two additional outpatient clinic appointments (n = 958 with at least one follow-up). In addition, a socio-demographically matched comparison group of individuals who were not hospitalized for psychiatric disorders (n = 149) was recruited from the surrounding catchment area. To summarize, a systematic review of the literature shows that the Signature Biobank has contributed to better characterizing psychiatric comorbidities, biological profiles, and psychosocial functioning across some of the most common psychiatric disorders, including psychosis, mood, anxiety, and substance use disorders. The Signature Biobank is now one of the world's largest repositories of data collected from patients receiving care at a psychiatric emergency unit.
KW - Biobanking
KW - Biological psychiatry
KW - Precision medicine
KW - Psychiatric diagnosis
KW - Psychometrics
KW - Recovery
UR - http://www.scopus.com/inward/record.url?scp=85182374444&partnerID=8YFLogxK
U2 - 10.1016/j.psychres.2024.115718
DO - 10.1016/j.psychres.2024.115718
M3 - Journal article
C2 - 38198857
AN - SCOPUS:85182374444
VL - 332
JO - Psychiatry Research
JF - Psychiatry Research
SN - 0165-1781
M1 - 115718
ER -
ID: 393779439