The search for putative unifying genetic factors for components of the metabolic syndrome
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The search for putative unifying genetic factors for components of the metabolic syndrome. / Sjögren, M; Lyssenko, V; Jonsson, Anna Elisabet; Berglund, G; Nilsson, P; Groop, L; Orho-Melander, M.
I: Diabetologia, Bind 51, Nr. 12, 12.2008, s. 2242-51.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - The search for putative unifying genetic factors for components of the metabolic syndrome
AU - Sjögren, M
AU - Lyssenko, V
AU - Jonsson, Anna Elisabet
AU - Berglund, G
AU - Nilsson, P
AU - Groop, L
AU - Orho-Melander, M
PY - 2008/12
Y1 - 2008/12
N2 - The metabolic syndrome is a cluster of factors contributing to increased risk of cardiovascular disease and type 2 diabetes but unifying mechanisms have not been identified. Our aim was to study whether common variations in 17 genes previously associated with type 2 diabetes or components of the metabolic syndrome and variants in nine genes with inconsistent association with at least two components of the metabolic syndrome would also predict future development of components of the metabolic syndrome, individually or in combination.
AB - The metabolic syndrome is a cluster of factors contributing to increased risk of cardiovascular disease and type 2 diabetes but unifying mechanisms have not been identified. Our aim was to study whether common variations in 17 genes previously associated with type 2 diabetes or components of the metabolic syndrome and variants in nine genes with inconsistent association with at least two components of the metabolic syndrome would also predict future development of components of the metabolic syndrome, individually or in combination.
KW - Diabetes Mellitus, Type 2
KW - Female
KW - Follow-Up Studies
KW - Genotype
KW - Humans
KW - Male
KW - Middle Aged
KW - Polymorphism, Single Nucleotide
KW - Risk Factors
U2 - 10.1007/s00125-008-1151-4
DO - 10.1007/s00125-008-1151-4
M3 - Journal article
C2 - 18853134
VL - 51
SP - 2242
EP - 2251
JO - Diabetologia
JF - Diabetologia
SN - 0012-186X
IS - 12
ER -
ID: 46404661