The influence of surface porosity on gap-healing around intra-articular implants in the presence of migrating particles
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The influence of surface porosity on gap-healing around intra-articular implants in the presence of migrating particles. / Rahbek, Ole; Kold, Soren; Zippor, Berit; Overgaard, Soren; Soballe, Kjeld.
I: Biomaterials, Bind 26, Nr. 23, 01.08.2005, s. 4728-36.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - The influence of surface porosity on gap-healing around intra-articular implants in the presence of migrating particles
AU - Rahbek, Ole
AU - Kold, Soren
AU - Zippor, Berit
AU - Overgaard, Soren
AU - Soballe, Kjeld
PY - 2005/8/1
Y1 - 2005/8/1
N2 - The aim of the present study was to compare the effect of two different porous coatings on bone ongrowth and on the peri-implant migration of polyethylene (PE) particles. Porous-coated cylindrical implants with an either plasma-sprayed closed-pore coating (Pl) or titanium fiber metal open-pore coating (Fi) were inserted intra-articular in exact fit or with a 0.75 mm peri-implant gap. A weight-loaded implant device in the distal femur was used. We used a randomized paired design in eight dogs. PE particles were injected repeatedly intra-articular in the knee until the dogs were killed after 8 weeks. Fi implants had significantly more bone ongrowth 8 (0-21)% compared with Pl implants 0 (0-0)% in gap situations and reduced the number of peri-implant PE particles significantly. Among exact-fitted implants we found that peri-implant tissue around Pl implants consisted of significantly more fibrous tissue than around Fi implants. A sealing effect against the migration of PE particles was found for both Fi and Pl implants in exact fit.
AB - The aim of the present study was to compare the effect of two different porous coatings on bone ongrowth and on the peri-implant migration of polyethylene (PE) particles. Porous-coated cylindrical implants with an either plasma-sprayed closed-pore coating (Pl) or titanium fiber metal open-pore coating (Fi) were inserted intra-articular in exact fit or with a 0.75 mm peri-implant gap. A weight-loaded implant device in the distal femur was used. We used a randomized paired design in eight dogs. PE particles were injected repeatedly intra-articular in the knee until the dogs were killed after 8 weeks. Fi implants had significantly more bone ongrowth 8 (0-21)% compared with Pl implants 0 (0-0)% in gap situations and reduced the number of peri-implant PE particles significantly. Among exact-fitted implants we found that peri-implant tissue around Pl implants consisted of significantly more fibrous tissue than around Fi implants. A sealing effect against the migration of PE particles was found for both Fi and Pl implants in exact fit.
U2 - 10.1016/j.biomaterials.2004.11.058
DO - 10.1016/j.biomaterials.2004.11.058
M3 - Journal article
C2 - 15763252
VL - 26
SP - 4728
EP - 4736
JO - Biomaterials
JF - Biomaterials
SN - 0142-9612
IS - 23
ER -
ID: 252057652