Temporal trends in revision rate due to knee periprosthetic joint infection: a study of 115,120 cases from the Danish Knee Arthroplasty Register
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Dokumenter
- Fulltext
Forlagets udgivne version, 1,26 MB, PDF-dokument
Patients and methods: 115,120 primary KA cases from the Danish Knee Arthroplasty Register were followed until the first PJI revision. We computed cumulative incidences and adjusted hazard ratios (aHRs) of PJI revision by calendar periods and several patient- and surgical-related risk factors. Results were analyzed from 0–3 months and from 3–12 months after KA.
Results: The overall 1-year PJI revision incidence was 0.7%, increasing from 0.5% to 0.7% (1997 through 2019). The incidence of PJI revision within 3 months increased from 0.1% to 0.5% (1997 through 2019). The adjusted hazard ratio (aHR) within 3 months of primary KA was 5.1 comparing 2017–2019 with 2001–2004. The PJI revision incidence from 3–12 months of KA decreased from 0.4% to 0.2%, with an aHR of 0.5 for 2017–2019 vs. 2001–2004. Male sex, age 75–84 (vs. 65–74), and extreme obesity (vs. normal weight) were positively associated with the risk of PJI revision within 3 months, whereas only male sex was associated from 3–12 months. Partial knee arthroplasty (PKA) vs. total KA was associated with a lower risk of PJI revision both within 3 months and 3–12 months of KA.
Conclusion: We observed an increase in PJI revision within 3 months of KA, and a decrease in PJI revision incidence from 3–12 months from 1997 through 2019. The reasons for this observed time-trend are thought to be multifactorial. PKA was associated with a lower risk of PJI revision.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Acta Orthopaedica |
Vol/bind | 94 |
Sider (fra-til) | 616-624 |
Antal sider | 9 |
ISSN | 1745-3674 |
DOI | |
Status | Udgivet - 2023 |
Eksternt udgivet | Ja |
Bibliografisk note
Funding Information:
The study was approved by the Danish Data Protection Agency (Record number AU-2016–051–000001, sequential number 880), and was funded by the Health Research Fund of Central Region Denmark and the Research Fund of the Institute of Clinical Medicine, Aarhus University, Denmark. The funders played no role in the investigation. Data was obtained specifically for this project, based on permissions required by the relevant Danish data authorities, which do not allow sharing of data with third parties. The authors declared no conflicts of interest. Complete disclosure of interest forms according to ICMJE are available on the article page, doi: 10.2340/17453674.2023.33294
Publisher Copyright:
© 2023 The Author(s). Published by Medical Journals Sweden, on behalf of the Nordic Orthopedic Federation.
ID: 396723415