Synthesis of dinucleoside phosphorodithioates via thioamidites
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Synthesis of dinucleoside phosphorodithioates via thioamidites. / Brill, Wolfgang K D; Nielsen, John; Caruthers, Marvin H.
I: Tetrahedron Letters, Bind 29, Nr. 43, 01.01.1988, s. 5517-5520.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Synthesis of dinucleoside phosphorodithioates via thioamidites
AU - Brill, Wolfgang K D
AU - Nielsen, John
AU - Caruthers, Marvin H.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - Deoxynucleosides and S-(4-chlorobenzyl)-phosphorothiodiamidites react via phosphorothioamidites to form thiophosphite triesters. Sulfur oxidation yields dinucleoside phosphorodithioate triesters which can be used to selectively introduce dithioate linkages into DNA.
AB - Deoxynucleosides and S-(4-chlorobenzyl)-phosphorothiodiamidites react via phosphorothioamidites to form thiophosphite triesters. Sulfur oxidation yields dinucleoside phosphorodithioate triesters which can be used to selectively introduce dithioate linkages into DNA.
U2 - 10.1016/S0040-4039(00)80801-1
DO - 10.1016/S0040-4039(00)80801-1
M3 - Journal article
AN - SCOPUS:0023737871
VL - 29
SP - 5517
EP - 5520
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 43
ER -
ID: 131116492