Syncope and Its Impact on Occupational Accidents and Employment: A Danish Nationwide Retrospective Cohort Study
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Syncope and Its Impact on Occupational Accidents and Employment : A Danish Nationwide Retrospective Cohort Study. / Numé, Anna-Karin; Kragholm, Kristian; Carlson, Nicolas; Kristensen, Søren L; Bøggild, Henrik; Hlatky, Mark A; Torp-Pedersen, Christian; Gislason, Gunnar; Ruwald, Martin H.
I: Circulation. Cardiovascular quality and outcomes, Bind 10, Nr. 4, e003202, 04.2017.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Syncope and Its Impact on Occupational Accidents and Employment
T2 - A Danish Nationwide Retrospective Cohort Study
AU - Numé, Anna-Karin
AU - Kragholm, Kristian
AU - Carlson, Nicolas
AU - Kristensen, Søren L
AU - Bøggild, Henrik
AU - Hlatky, Mark A
AU - Torp-Pedersen, Christian
AU - Gislason, Gunnar
AU - Ruwald, Martin H
N1 - © 2017 American Heart Association, Inc.
PY - 2017/4
Y1 - 2017/4
N2 - BACKGROUND: First-time syncopal episodes usually occur in adults of working age, but their impact on occupational safety and employment remains unknown. We examined the associations of syncope with occupational accidents and termination of employment.METHODS AND RESULTS: Through linkage of Danish population-based registers, we included all residents 18 to 64 years from 2008 to 2012. Among 3 410 148 eligible individuals, 21 729 with a first-time diagnosis of syncope were identified, with a median age 48.4 years (first to third quartiles, 33.0-59.5), and 10 757 (49.5%) employed at time of the syncope event. Over a median follow-up of 3.2 years (first to third quartiles, 2.0-4.5), 622 people with syncope had an occupational accident requiring hospitalization (2.1/100 person-years). In multiple Poisson regression analysis, the incidence rate ratio in the employed syncope population was higher than in the employed general population (1.44; 95% confidence interval [CI], 1.33-1.55) and more pronounced in people with recurrences (2.02; 95% CI, 1.47-2.78). The 2-year risk of termination of employment was 31.3% (95% CI, 30.4%-32.3%), which was twice the risk of the reference population (15.2%; 95% CI, 14.7%-15.7%), using the Aalen-Johansen estimator. Factors associated with termination of employment were age <40 years (incidence rate ratio, 1.48; 95% CI, 1.37-1.59), cardiovascular disease (1.20; 95% CI, 1.06-1.36), depression (1.72; 95% CI, 1.55-1.90), and low educational level (2.61; 95% CI, 2.34-2.91).CONCLUSIONS: In this nationwide cohort, syncope was associated with a 1.4-fold higher risk of occupational accidents and a 2-fold higher risk of termination of employment compared with the employed general population.
AB - BACKGROUND: First-time syncopal episodes usually occur in adults of working age, but their impact on occupational safety and employment remains unknown. We examined the associations of syncope with occupational accidents and termination of employment.METHODS AND RESULTS: Through linkage of Danish population-based registers, we included all residents 18 to 64 years from 2008 to 2012. Among 3 410 148 eligible individuals, 21 729 with a first-time diagnosis of syncope were identified, with a median age 48.4 years (first to third quartiles, 33.0-59.5), and 10 757 (49.5%) employed at time of the syncope event. Over a median follow-up of 3.2 years (first to third quartiles, 2.0-4.5), 622 people with syncope had an occupational accident requiring hospitalization (2.1/100 person-years). In multiple Poisson regression analysis, the incidence rate ratio in the employed syncope population was higher than in the employed general population (1.44; 95% confidence interval [CI], 1.33-1.55) and more pronounced in people with recurrences (2.02; 95% CI, 1.47-2.78). The 2-year risk of termination of employment was 31.3% (95% CI, 30.4%-32.3%), which was twice the risk of the reference population (15.2%; 95% CI, 14.7%-15.7%), using the Aalen-Johansen estimator. Factors associated with termination of employment were age <40 years (incidence rate ratio, 1.48; 95% CI, 1.37-1.59), cardiovascular disease (1.20; 95% CI, 1.06-1.36), depression (1.72; 95% CI, 1.55-1.90), and low educational level (2.61; 95% CI, 2.34-2.91).CONCLUSIONS: In this nationwide cohort, syncope was associated with a 1.4-fold higher risk of occupational accidents and a 2-fold higher risk of termination of employment compared with the employed general population.
KW - Accidents, Occupational
KW - Adolescent
KW - Adult
KW - Age Factors
KW - Cardiovascular Diseases/epidemiology
KW - Comorbidity
KW - Denmark/epidemiology
KW - Depression/epidemiology
KW - Educational Status
KW - Employment
KW - Female
KW - Hospitalization
KW - Humans
KW - Incidence
KW - Male
KW - Middle Aged
KW - Occupational Health
KW - Registries
KW - Retrospective Studies
KW - Risk Assessment
KW - Risk Factors
KW - Syncope/diagnosis
KW - Young Adult
U2 - 10.1161/CIRCOUTCOMES.116.003202
DO - 10.1161/CIRCOUTCOMES.116.003202
M3 - Journal article
C2 - 28420655
VL - 10
JO - Circulation: Cardiovascular Quality and Outcomes
JF - Circulation: Cardiovascular Quality and Outcomes
SN - 1941-7713
IS - 4
M1 - e003202
ER -
ID: 196004121