Suicide and mental illness in parents and risk of suicide in offspring: a birth cohort study
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Suicide and mental illness in parents and risk of suicide in offspring: a birth cohort study. / Sørensen, Holger J; Mortensen, Erik L; Wang, August G; Juel, Knud; Silverton, Leigh; Mednick, Sarnoff A.
I: Social Psychiatry and Psychiatric Epidemiology, Bind 44, Nr. 9, 2009, s. 748-51.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Suicide and mental illness in parents and risk of suicide in offspring: a birth cohort study
AU - Sørensen, Holger J
AU - Mortensen, Erik L
AU - Wang, August G
AU - Juel, Knud
AU - Silverton, Leigh
AU - Mednick, Sarnoff A
N1 - Keywords: Adult; Adult Children; Cause of Death; Child; Child of Impaired Parents; Cohort Studies; Denmark; Fathers; Female; Hospitalization; Hospitals, Psychiatric; Humans; Male; Mental Disorders; Mothers; Registries; Risk Factors; Sex Factors; Suicide
PY - 2009
Y1 - 2009
N2 - BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adult offspring born 1959-1961 and their parents from the Copenhagen Perinatal Cohort. Cohort members and their parents who had committed suicide were identified in the Danish Causes of Death Registry (follow-up until December 31, 2005), while information on psychiatric hospitalisation history was obtained from the Danish Psychiatric Central Research Register. RESULTS: Forty-eight cohort members, 77 mothers and 133 fathers had committed suicide during the follow-up. Independent of parental psychiatric illness and social status, parental suicide significantly increased suicide risk in offspring (hazard ratio 4.40 with 95% CI 1.81-10.69). A stronger effect of parental suicide was observed in offspring without a history of psychiatric hospitalisation. CONCLUSION: Parental history of suicide is a risk factor for suicide in offspring, but primarily in offspring without psychiatric hospitalisation.
AB - BACKGROUND: A family history of completed suicide and psychiatric illness has been identified as risk factors for suicide. AIMS: To examine the risk of offspring suicide in relation to parental history of suicide and other parental risk factors. METHOD: The study population consisted of 7,177 adult offspring born 1959-1961 and their parents from the Copenhagen Perinatal Cohort. Cohort members and their parents who had committed suicide were identified in the Danish Causes of Death Registry (follow-up until December 31, 2005), while information on psychiatric hospitalisation history was obtained from the Danish Psychiatric Central Research Register. RESULTS: Forty-eight cohort members, 77 mothers and 133 fathers had committed suicide during the follow-up. Independent of parental psychiatric illness and social status, parental suicide significantly increased suicide risk in offspring (hazard ratio 4.40 with 95% CI 1.81-10.69). A stronger effect of parental suicide was observed in offspring without a history of psychiatric hospitalisation. CONCLUSION: Parental history of suicide is a risk factor for suicide in offspring, but primarily in offspring without psychiatric hospitalisation.
U2 - http://dx.doi.org/10.1007/s00127-009-0495-5
DO - http://dx.doi.org/10.1007/s00127-009-0495-5
M3 - Journal article
VL - 44
SP - 748
EP - 751
JO - Social Psychiatry and Psychiatric Epidemiology
JF - Social Psychiatry and Psychiatric Epidemiology
SN - 0933-7954
IS - 9
ER -
ID: 40197666