Submikroskopiske kromosomanomalier som årsag til skizofreni
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Submikroskopiske kromosomanomalier som årsag til skizofreni. / Hansen, Thomas; Ingason, Andrés; Werge, Thomas.
I: Ugeskrift for Laeger, Bind 170, Nr. 46, 2008, s. 3773-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Submikroskopiske kromosomanomalier som årsag til skizofreni
AU - Hansen, Thomas
AU - Ingason, Andrés
AU - Werge, Thomas
PY - 2008
Y1 - 2008
N2 - Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.
AB - Although the inheritable nature of schizophrenia is well-established, the genetic underpinnings remain largely hidden. Recently, two independent research groups identified microdeletions conferring high risk of schizophrenia. The deletions are recurrent in nature and offer an explanation to the apparently stable prevalence of the disease, despite reduced fecundity in patients. The findings may lead to development of diagnostic tools and construction of new disease models to help the development of novel therapeutic strategies.
M3 - Tidsskriftartikel
VL - 170
SP - 3773
EP - 3776
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 46
ER -
ID: 48610787