Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida

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Standard

Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida. / Sittie, A A; Lemmich, E; Olsen, C E; Hviid, L; Kharazmi, A; Nkrumah, F K; Christensen, S B.

I: Planta Medica, Bind 65, Nr. 3, 1999, s. 259-61.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Sittie, AA, Lemmich, E, Olsen, CE, Hviid, L, Kharazmi, A, Nkrumah, FK & Christensen, SB 1999, 'Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida', Planta Medica, bind 65, nr. 3, s. 259-61.

APA

Sittie, A. A., Lemmich, E., Olsen, C. E., Hviid, L., Kharazmi, A., Nkrumah, F. K., & Christensen, S. B. (1999). Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida. Planta Medica, 65(3), 259-61.

Vancouver

Sittie AA, Lemmich E, Olsen CE, Hviid L, Kharazmi A, Nkrumah FK o.a. Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida. Planta Medica. 1999;65(3):259-61.

Author

Sittie, A A ; Lemmich, E ; Olsen, C E ; Hviid, L ; Kharazmi, A ; Nkrumah, F K ; Christensen, S B. / Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida. I: Planta Medica. 1999 ; Bind 65, Nr. 3. s. 259-61.

Bibtex

@article{6f6170d0a06911dd86a6000ea68e967b,

title = "Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida",

abstract = "Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.",

author = "Sittie, {A A} and E Lemmich and Olsen, {C E} and L Hviid and A Kharazmi and Nkrumah, {F K} and Christensen, {S B}",

note = "Keywords: Animals; Anthraquinones; Antimalarials; Antiprotozoal Agents; Leishmania major; Plasmodium falciparum; Rubiaceae; Structure-Activity Relationship",

year = "1999",

language = "English",

volume = "65",

pages = "259--61",

journal = "Planta Medica",

issn = "0032-0943",

publisher = "GeorgThieme Verlag",

number = "3",

}

RIS

TY - JOUR

T1 - Structure-activity studies: in vitro antileishmanial and antimalarial activities of anthraquinones from Morinda lucida

AU - Sittie, A A

AU - Lemmich, E

AU - Olsen, C E

AU - Hviid, L

AU - Kharazmi, A

AU - Nkrumah, F K

AU - Christensen, S B

N1 - Keywords: Animals; Anthraquinones; Antimalarials; Antiprotozoal Agents; Leishmania major; Plasmodium falciparum; Rubiaceae; Structure-Activity Relationship

PY - 1999

Y1 - 1999

N2 - Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.

AB - Anthraquinones have been isolated by bioassay-guided fractionation from Morinda lucida. Structure-activity studies show that an aldehyde group at C-2 and a phenolic hydroxy group at C-3 enhance the activity of the anthraquinones against the growth of Plasmodium falciparum and promastigotes of Leishmania major in vitro.

M3 - Journal article

C2 - 10232074

VL - 65

SP - 259

EP - 261

JO - Planta Medica

JF - Planta Medica

SN - 0032-0943

IS - 3

ER -

ID: 6748028