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Risk of triple-class virological failure in children with HIV: a retrospective cohort study. / Castro, Hannah; Judd, Ali; Gibb, Diana M; Butler, Karina; Lodwick, Rebecca K; van Sighem, Ard; Ramos, Jose T; Warsawski, Josiane; Thorne, Claire; Noguera-Julian, Antoni; Obel, Niels; Costagliola, Dominique; Tookey, Pat A; Colin, Céline; Kjaer, Jesper; Grarup, Jesper; Chene, Genevieve; Phillips, Andrew; Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE).
I:
Lancet, Bind 377, Nr. 9777, 07.05.2011, s. 1580-7.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Castro, H, Judd, A, Gibb, DM, Butler, K, Lodwick, RK, van Sighem, A, Ramos, JT, Warsawski, J, Thorne, C, Noguera-Julian, A
, Obel, N, Costagliola, D, Tookey, PA, Colin, C, Kjaer, J, Grarup, J, Chene, G, Phillips, A & Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) 2011, '
Risk of triple-class virological failure in children with HIV: a retrospective cohort study',
Lancet, bind 377, nr. 9777, s. 1580-7.
https://doi.org/10.1016/S0140-6736(11)60208-0APA
Castro, H., Judd, A., Gibb, D. M., Butler, K., Lodwick, R. K., van Sighem, A., Ramos, J. T., Warsawski, J., Thorne, C., Noguera-Julian, A.
, Obel, N., Costagliola, D., Tookey, P. A., Colin, C., Kjaer, J., Grarup, J., Chene, G., Phillips, A., & Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) (2011).
Risk of triple-class virological failure in children with HIV: a retrospective cohort study.
Lancet,
377(9777), 1580-7.
https://doi.org/10.1016/S0140-6736(11)60208-0Vancouver
Castro H, Judd A, Gibb DM, Butler K, Lodwick RK, van Sighem A o.a.
Risk of triple-class virological failure in children with HIV: a retrospective cohort study.
Lancet. 2011 maj 7;377(9777):1580-7.
https://doi.org/10.1016/S0140-6736(11)60208-0Author
Castro, Hannah ; Judd, Ali ; Gibb, Diana M ; Butler, Karina ; Lodwick, Rebecca K ; van Sighem, Ard ; Ramos, Jose T ; Warsawski, Josiane ; Thorne, Claire ; Noguera-Julian, Antoni ; Obel, Niels ; Costagliola, Dominique ; Tookey, Pat A ; Colin, Céline ; Kjaer, Jesper ; Grarup, Jesper ; Chene, Genevieve ; Phillips, Andrew ; Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE). / Risk of triple-class virological failure in children with HIV: a retrospective cohort study. I: Lancet. 2011 ; Bind 377, Nr. 9777. s. 1580-7.
Bibtex
@article{99e2fc61b74d47c49ec151e23c206894,
title = "Risk of triple-class virological failure in children with HIV: a retrospective cohort study",
abstract = "In adults with HIV treated with antiretroviral drug regimens from within the three original drug classes (nucleoside or nucleotide reverse transcriptase inhibitors [NRTIs], non-NRTIs [NNRTIs], and protease inhibitors), virological failure occurs slowly, suggesting that long-term virological suppression can be achieved in most people, even in areas where access is restricted to drugs from these classes. It is unclear whether this is the case for children, the group who will need to maintain viral suppression for longest. We aimed to determine the rate and predictors of triple-class virological failure to the three original drugs classes in children.",
keywords = "Adolescent, Anti-Retroviral Agents, Child, Child, Preschool, Cohort Studies, Female, HIV Infections, Humans, Infant, Infectious Disease Transmission, Vertical, Kaplan-Meier Estimate, Male, Proportional Hazards Models, Retrospective Studies, Risk, Treatment Failure, Viral Load",
author = "Hannah Castro and Ali Judd and Gibb, {Diana M} and Karina Butler and Lodwick, {Rebecca K} and {van Sighem}, Ard and Ramos, {Jose T} and Josiane Warsawski and Claire Thorne and Antoni Noguera-Julian and Niels Obel and Dominique Costagliola and Tookey, {Pat A} and C{\'e}line Colin and Jesper Kjaer and Jesper Grarup and Genevieve Chene and Andrew Phillips and {Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE)}",
note = "Copyright {\textcopyright} 2011 Elsevier Ltd. All rights reserved.",
year = "2011",
month = may,
day = "7",
doi = "10.1016/S0140-6736(11)60208-0",
language = "English",
volume = "377",
pages = "1580--7",
journal = "The Lancet",
issn = "0140-6736",
publisher = "TheLancet Publishing Group",
number = "9777",
}
RIS
TY - JOUR
T1 - Risk of triple-class virological failure in children with HIV: a retrospective cohort study
AU - Castro, Hannah
AU - Judd, Ali
AU - Gibb, Diana M
AU - Butler, Karina
AU - Lodwick, Rebecca K
AU - van Sighem, Ard
AU - Ramos, Jose T
AU - Warsawski, Josiane
AU - Thorne, Claire
AU - Noguera-Julian, Antoni
AU - Obel, Niels
AU - Costagliola, Dominique
AU - Tookey, Pat A
AU - Colin, Céline
AU - Kjaer, Jesper
AU - Grarup, Jesper
AU - Chene, Genevieve
AU - Phillips, Andrew
AU - Pursuing Later Treatment Options II (PLATO II) project team for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE)
N1 - Copyright © 2011 Elsevier Ltd. All rights reserved.
PY - 2011/5/7
Y1 - 2011/5/7
N2 - In adults with HIV treated with antiretroviral drug regimens from within the three original drug classes (nucleoside or nucleotide reverse transcriptase inhibitors [NRTIs], non-NRTIs [NNRTIs], and protease inhibitors), virological failure occurs slowly, suggesting that long-term virological suppression can be achieved in most people, even in areas where access is restricted to drugs from these classes. It is unclear whether this is the case for children, the group who will need to maintain viral suppression for longest. We aimed to determine the rate and predictors of triple-class virological failure to the three original drugs classes in children.
AB - In adults with HIV treated with antiretroviral drug regimens from within the three original drug classes (nucleoside or nucleotide reverse transcriptase inhibitors [NRTIs], non-NRTIs [NNRTIs], and protease inhibitors), virological failure occurs slowly, suggesting that long-term virological suppression can be achieved in most people, even in areas where access is restricted to drugs from these classes. It is unclear whether this is the case for children, the group who will need to maintain viral suppression for longest. We aimed to determine the rate and predictors of triple-class virological failure to the three original drugs classes in children.
KW - Adolescent
KW - Anti-Retroviral Agents
KW - Child
KW - Child, Preschool
KW - Cohort Studies
KW - Female
KW - HIV Infections
KW - Humans
KW - Infant
KW - Infectious Disease Transmission, Vertical
KW - Kaplan-Meier Estimate
KW - Male
KW - Proportional Hazards Models
KW - Retrospective Studies
KW - Risk
KW - Treatment Failure
KW - Viral Load
U2 - 10.1016/S0140-6736(11)60208-0
DO - 10.1016/S0140-6736(11)60208-0
M3 - Journal article
C2 - 21511330
VL - 377
SP - 1580
EP - 1587
JO - The Lancet
JF - The Lancet
SN - 0140-6736
IS - 9777
ER -
