Risk of Psychiatric Disorders, Use of Psychiatric Hospitals, and Receipt of Psychiatric Medication in Patients With Brain Abscess in Denmark
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Risk of Psychiatric Disorders, Use of Psychiatric Hospitals, and Receipt of Psychiatric Medication in Patients With Brain Abscess in Denmark. / Omland, Lars Haukali; Bodilsen, Jacob; Tetens, Malte Mose; Helweg-Larsen, Jannik; Jarløv, Jens Otto; Ziebell, Morten; Ellermann-Eriksen, Svend; Justesen, Ulrik Stenz; Frimodt-Møller, Niels; Mortensen, Preben Bo; Obel, Niels.
I: Clinical Infectious Diseases, Bind 76, Nr. 2, 2023, s. 315-322.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Risk of Psychiatric Disorders, Use of Psychiatric Hospitals, and Receipt of Psychiatric Medication in Patients With Brain Abscess in Denmark
AU - Omland, Lars Haukali
AU - Bodilsen, Jacob
AU - Tetens, Malte Mose
AU - Helweg-Larsen, Jannik
AU - Jarløv, Jens Otto
AU - Ziebell, Morten
AU - Ellermann-Eriksen, Svend
AU - Justesen, Ulrik Stenz
AU - Frimodt-Møller, Niels
AU - Mortensen, Preben Bo
AU - Obel, Niels
N1 - Publisher Copyright: © 2022 The Author(s).
PY - 2023
Y1 - 2023
N2 - Background: It is unknown whether patients diagnosed with brain abscess have an increased risk of psychiatric disorders. Methods: In this nationwide, population-based matched cohort study from Denmark, we compared the incidence of psychiatric disorders, use of psychiatric hospitals, and receipt of psychiatric medications between patients diagnosed with brain abscess and individuals from the general population, matched on date of birth, sex, and residential area. Results: We included 435 patients diagnosed with brain abscess and 3909 individuals in the comparison cohort: 61% were male and median age was 54 years. Patients diagnosed with brain abscess were more likely to suffer from comorbidity. The risk of a hospital diagnosis of psychiatric disorders was increased the first 5 years of observation. In the subpopulation, who had never been in contact with psychiatric hospitals or received psychiatric medication before study inclusion, the risk of developing psychiatric disorders was close to that of the background population, especially when we excluded dementia from this outcome. There was a substantial increase in the receipt of anxiolytics and antidepressants. The difference in the proportion of individuals who received anxiolytics and antidepressants increased from 4% (95% confidence interval [CI], 0%-7%) and 2% (95% CI, -1% to 5%) 2 years before study inclusion to 17% (95% CI, 12%-21%) and 11% (95% CI, 7%-16%) in the year after study inclusion. Conclusions: Patients with brain abscess without prior psychiatric disorders or receipt of psychiatric medicine are not at increased risk psychiatric disorders diagnosed in psychiatric hospitals, but they have an increased receipt of psychiatric medication.
AB - Background: It is unknown whether patients diagnosed with brain abscess have an increased risk of psychiatric disorders. Methods: In this nationwide, population-based matched cohort study from Denmark, we compared the incidence of psychiatric disorders, use of psychiatric hospitals, and receipt of psychiatric medications between patients diagnosed with brain abscess and individuals from the general population, matched on date of birth, sex, and residential area. Results: We included 435 patients diagnosed with brain abscess and 3909 individuals in the comparison cohort: 61% were male and median age was 54 years. Patients diagnosed with brain abscess were more likely to suffer from comorbidity. The risk of a hospital diagnosis of psychiatric disorders was increased the first 5 years of observation. In the subpopulation, who had never been in contact with psychiatric hospitals or received psychiatric medication before study inclusion, the risk of developing psychiatric disorders was close to that of the background population, especially when we excluded dementia from this outcome. There was a substantial increase in the receipt of anxiolytics and antidepressants. The difference in the proportion of individuals who received anxiolytics and antidepressants increased from 4% (95% confidence interval [CI], 0%-7%) and 2% (95% CI, -1% to 5%) 2 years before study inclusion to 17% (95% CI, 12%-21%) and 11% (95% CI, 7%-16%) in the year after study inclusion. Conclusions: Patients with brain abscess without prior psychiatric disorders or receipt of psychiatric medicine are not at increased risk psychiatric disorders diagnosed in psychiatric hospitals, but they have an increased receipt of psychiatric medication.
KW - brain abscess
KW - cohort study
KW - psychiatric disorders
KW - psychiatric medication
U2 - 10.1093/cid/ciac773
DO - 10.1093/cid/ciac773
M3 - Journal article
C2 - 36124707
AN - SCOPUS:85146365245
VL - 76
SP - 315
EP - 322
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 2
ER -
ID: 363279251