Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study

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Standard

Psoriasis and New-onset Depression : A Danish Nationwide Cohort Study. / Jensen, Peter; Ahlehoff, Ole; Egeberg, Alexander; Gislason, Gunnar; Hansen, Peter R; Skov, Lone.

I: Acta Dermato-Venereologica, Bind 96, Nr. 1, 2016, s. 39-42.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jensen, P, Ahlehoff, O, Egeberg, A, Gislason, G, Hansen, PR & Skov, L 2016, 'Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study', Acta Dermato-Venereologica, bind 96, nr. 1, s. 39-42. https://doi.org/10.2340/00015555-2183

APA

Jensen, P., Ahlehoff, O., Egeberg, A., Gislason, G., Hansen, P. R., & Skov, L. (2016). Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study. Acta Dermato-Venereologica, 96(1), 39-42. https://doi.org/10.2340/00015555-2183

Vancouver

Jensen P, Ahlehoff O, Egeberg A, Gislason G, Hansen PR, Skov L. Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study. Acta Dermato-Venereologica. 2016;96(1):39-42. https://doi.org/10.2340/00015555-2183

Author

Jensen, Peter ; Ahlehoff, Ole ; Egeberg, Alexander ; Gislason, Gunnar ; Hansen, Peter R ; Skov, Lone. / Psoriasis and New-onset Depression : A Danish Nationwide Cohort Study. I: Acta Dermato-Venereologica. 2016 ; Bind 96, Nr. 1. s. 39-42.

Bibtex

@article{f3cb843ef9b542e79b3ad2a19df2e114,
title = "Psoriasis and New-onset Depression: A Danish Nationwide Cohort Study",
abstract = "Psoriasis is associated with an increased risk of depression, but results are inconsistent. This study examined the risk of new-onset depression in patients with psoriasis in a nationwide Danish cohort including some 5 million people in the period 2001-2011. A total of 35,001 patients with mild psoriasis and 7,510 with severe psoriasis were identified. Incidence rates per 1,000 person-years and incidence rate ratios (IRRs) were calculated. Incidence rates for depression were 20.0 (95% confidence interval 19.9-20.0), 23.9 (23.1-24.7) and 31.6 (29.5-33.8) for the reference population, mild, and severe psoriasis, respectively. Adjusted for age, sex, and inclusion year, IRRs were 1.08 (1.04-1.12) in mild and 1.36 (1.27-1.46) in severe psoriasis. After adjustment for comorbidity, the IRR was significant in only patients < 50 years with severe psoriasis (IRR 1.23 (1.03-1.46)). In conclusion, the risk of new-onset depression in psoriasis is mediated primarily by comorbidities, except in younger individuals with severe psoriasis, in whom psoriasis itself may be a risk factor.",
author = "Peter Jensen and Ole Ahlehoff and Alexander Egeberg and Gunnar Gislason and Hansen, {Peter R} and Lone Skov",
year = "2016",
doi = "10.2340/00015555-2183",
language = "English",
volume = "96",
pages = "39--42",
journal = "Acta Dermato-Venereologica",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato - Venereologica",
number = "1",

}

RIS

TY - JOUR

T1 - Psoriasis and New-onset Depression

T2 - A Danish Nationwide Cohort Study

AU - Jensen, Peter

AU - Ahlehoff, Ole

AU - Egeberg, Alexander

AU - Gislason, Gunnar

AU - Hansen, Peter R

AU - Skov, Lone

PY - 2016

Y1 - 2016

N2 - Psoriasis is associated with an increased risk of depression, but results are inconsistent. This study examined the risk of new-onset depression in patients with psoriasis in a nationwide Danish cohort including some 5 million people in the period 2001-2011. A total of 35,001 patients with mild psoriasis and 7,510 with severe psoriasis were identified. Incidence rates per 1,000 person-years and incidence rate ratios (IRRs) were calculated. Incidence rates for depression were 20.0 (95% confidence interval 19.9-20.0), 23.9 (23.1-24.7) and 31.6 (29.5-33.8) for the reference population, mild, and severe psoriasis, respectively. Adjusted for age, sex, and inclusion year, IRRs were 1.08 (1.04-1.12) in mild and 1.36 (1.27-1.46) in severe psoriasis. After adjustment for comorbidity, the IRR was significant in only patients < 50 years with severe psoriasis (IRR 1.23 (1.03-1.46)). In conclusion, the risk of new-onset depression in psoriasis is mediated primarily by comorbidities, except in younger individuals with severe psoriasis, in whom psoriasis itself may be a risk factor.

AB - Psoriasis is associated with an increased risk of depression, but results are inconsistent. This study examined the risk of new-onset depression in patients with psoriasis in a nationwide Danish cohort including some 5 million people in the period 2001-2011. A total of 35,001 patients with mild psoriasis and 7,510 with severe psoriasis were identified. Incidence rates per 1,000 person-years and incidence rate ratios (IRRs) were calculated. Incidence rates for depression were 20.0 (95% confidence interval 19.9-20.0), 23.9 (23.1-24.7) and 31.6 (29.5-33.8) for the reference population, mild, and severe psoriasis, respectively. Adjusted for age, sex, and inclusion year, IRRs were 1.08 (1.04-1.12) in mild and 1.36 (1.27-1.46) in severe psoriasis. After adjustment for comorbidity, the IRR was significant in only patients < 50 years with severe psoriasis (IRR 1.23 (1.03-1.46)). In conclusion, the risk of new-onset depression in psoriasis is mediated primarily by comorbidities, except in younger individuals with severe psoriasis, in whom psoriasis itself may be a risk factor.

U2 - 10.2340/00015555-2183

DO - 10.2340/00015555-2183

M3 - Journal article

C2 - 26086213

VL - 96

SP - 39

EP - 42

JO - Acta Dermato-Venereologica

JF - Acta Dermato-Venereologica

SN - 0001-5555

IS - 1

ER -

ID: 162647895