Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise
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Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise. / Ashcroft, Stephen P; Jepsen, Sara L; Ehrlich, Amy M; Treebak, Jonas T; Holst, Jens J; Zierath, Juleen R.
I: STAR Protocols, Bind 4, Nr. 1, 101985, 2023.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise
AU - Ashcroft, Stephen P
AU - Jepsen, Sara L
AU - Ehrlich, Amy M
AU - Treebak, Jonas T
AU - Holst, Jens J
AU - Zierath, Juleen R
N1 - Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.
PY - 2023
Y1 - 2023
N2 - The tissue-specific release and uptake of metabolites in response to exercise is incompletely understood. Here, we detail a protocol to assess arteriovenous differences across the liver and hindlimb muscles in response to treadmill exercise in mice. We describe steps for the treadmill running of mice and the region-specific sampling of blood from the liver and hindlimb. This procedure is particularly relevant for the study of tissue-specific metabolism in response to exercise. For complete details on the use and execution of this protocol, please refer to Sato et al. (2022). 1.
AB - The tissue-specific release and uptake of metabolites in response to exercise is incompletely understood. Here, we detail a protocol to assess arteriovenous differences across the liver and hindlimb muscles in response to treadmill exercise in mice. We describe steps for the treadmill running of mice and the region-specific sampling of blood from the liver and hindlimb. This procedure is particularly relevant for the study of tissue-specific metabolism in response to exercise. For complete details on the use and execution of this protocol, please refer to Sato et al. (2022). 1.
U2 - 10.1016/j.xpro.2022.101985
DO - 10.1016/j.xpro.2022.101985
M3 - Journal article
C2 - 36602899
VL - 4
JO - STAR Protocols
JF - STAR Protocols
SN - 2666-1667
IS - 1
M1 - 101985
ER -
ID: 333435470