Prognostic scoring models in parotid gland carcinoma
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- Prognostic scoring models in parotid gland carcinoma
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Background: The aim was to identify prognostic factors and test three prognostic scoring models that predicted the risk of recurrence in patients with parotid gland carcinoma. Methods: All Danish patients with parotid gland carcinoma, treated with curative intent, from 1990 to 2015 (n = 726) were included. Potential prognostic factors were evaluated using Cox regression and competing risk analyses. The concordance of each prognostic model was estimated using Harrel's C index. Results: The study population consisted of 344 men and 382 women, with a median age of 63 years. Age above 60 years, high grade histology, T3/T4 tumor, regional lymph node metastases, and involved surgical margins were all associated with a significant reduction in recurrence-free survival. The prognostic model that agreed best with actual outcomes had a C-index of 0.76. Conclusion: Prognostic scoring models may improve individualized follow-up strategies after curatively intended treatment for patients with parotid gland carcinoma.
Originalsprog | Engelsk |
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Tidsskrift | Head and Neck |
Vol/bind | 43 |
Udgave nummer | 7 |
Sider (fra-til) | 2081-2090 |
Antal sider | 10 |
ISSN | 1043-3074 |
DOI | |
Status | Udgivet - jul. 2021 |
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© 2021 Wiley Periodicals LLC.
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