Physical mapping and cloning of RAD56
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Here we report the physical mapping of the rad56-1 mutation to the NAT3 gene, which encodes the catalytic subunit of the NatB N-terminal acetyltransferase in Saccharomyces cerevisiae. Mutation of RAD56 causes sensitivity to X-rays, methyl methanesulfonate, zeocin, camptothecin and hydroxyurea, but not to UV light, suggesting that N-terminal acetylation of specific DNA repair proteins is important for efficient DNA repair.
Bidragets oversatte titel | Fysisk kortlægning og klonering af RAD56 |
---|---|
Originalsprog | Engelsk |
Tidsskrift | Gene |
Vol/bind | 519 |
Udgave nummer | 1 |
Sider (fra-til) | 182-186 |
Antal sider | 5 |
ISSN | 0378-1119 |
DOI | |
Status | Udgivet - 25 apr. 2013 |
ID: 45275731