Persistent Topology of Protein Space
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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Persistent Topology of Protein Space. / Hamilton, W.; Borgert, J. E.; Hamelryck, T.; Marron, J. S.
Research in Computational Topology 2. Springer, 2022. s. 223-244 (Association for Women in Mathematics Series, Bind 30).Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Persistent Topology of Protein Space
AU - Hamilton, W.
AU - Borgert, J. E.
AU - Hamelryck, T.
AU - Marron, J. S.
N1 - Publisher Copyright: © 2022, The Author(s) and the Association for Women in Mathematics.
PY - 2022
Y1 - 2022
N2 - Protein fold classification is a classic problem in structural biology and bioinformatics. We approach this problem using persistent homology. In particular, we use alpha shape filtrations to compare a topological representation of the data with a different representation that makes use of knot-theoretic ideas. We use the statistical method of Angle-based Joint and Individual Variation Explained (AJIVE) to understand similarities and differences between these representations.
AB - Protein fold classification is a classic problem in structural biology and bioinformatics. We approach this problem using persistent homology. In particular, we use alpha shape filtrations to compare a topological representation of the data with a different representation that makes use of knot-theoretic ideas. We use the statistical method of Angle-based Joint and Individual Variation Explained (AJIVE) to understand similarities and differences between these representations.
UR - http://www.scopus.com/inward/record.url?scp=85130525097&partnerID=8YFLogxK
U2 - 10.1007/978-3-030-95519-9_10
DO - 10.1007/978-3-030-95519-9_10
M3 - Book chapter
AN - SCOPUS:85130525097
SN - 978-3-030-95518-2
T3 - Association for Women in Mathematics Series
SP - 223
EP - 244
BT - Research in Computational Topology 2
PB - Springer
ER -
ID: 309122829