Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes. / Jensen, Dorte M; Korsholm, Lars; Ovesen, Per; Beck-Nielsen, Henning; Moelsted-Pedersen, Lars; Westergaard, Jes G; Moeller, Margrethe; Damm, Peter; Jensen, Dorte; Lauridsen, Lars Korsholm; Ovesen, Per Glud; Beck-Nielsen, Henning; Moelsted-Pedersen, Lars; Westergaard, Jes G; Moeller, Margrethe; Damm, Peter.

I: Diabetes Care, Bind 32, Nr. 6, 01.06.2009, s. 1046-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jensen, DM, Korsholm, L, Ovesen, P, Beck-Nielsen, H, Moelsted-Pedersen, L, Westergaard, JG, Moeller, M, Damm, P, Jensen, D, Lauridsen, LK, Ovesen, PG, Beck-Nielsen, H, Moelsted-Pedersen, L, Westergaard, JG, Moeller, M & Damm, P 2009, 'Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes', Diabetes Care, bind 32, nr. 6, s. 1046-8. https://doi.org/10.2337/dc08-2061, https://doi.org/10.2337/dc08-2061

APA

Jensen, D. M., Korsholm, L., Ovesen, P., Beck-Nielsen, H., Moelsted-Pedersen, L., Westergaard, J. G., Moeller, M., Damm, P., Jensen, D., Lauridsen, L. K., Ovesen, P. G., Beck-Nielsen, H., Moelsted-Pedersen, L., Westergaard, J. G., Moeller, M., & Damm, P. (2009). Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes. Diabetes Care, 32(6), 1046-8. https://doi.org/10.2337/dc08-2061, https://doi.org/10.2337/dc08-2061

Vancouver

Jensen DM, Korsholm L, Ovesen P, Beck-Nielsen H, Moelsted-Pedersen L, Westergaard JG o.a. Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes. Diabetes Care. 2009 jun. 1;32(6):1046-8. https://doi.org/10.2337/dc08-2061, https://doi.org/10.2337/dc08-2061

Author

Jensen, Dorte M ; Korsholm, Lars ; Ovesen, Per ; Beck-Nielsen, Henning ; Moelsted-Pedersen, Lars ; Westergaard, Jes G ; Moeller, Margrethe ; Damm, Peter ; Jensen, Dorte ; Lauridsen, Lars Korsholm ; Ovesen, Per Glud ; Beck-Nielsen, Henning ; Moelsted-Pedersen, Lars ; Westergaard, Jes G ; Moeller, Margrethe ; Damm, Peter. / Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes. I: Diabetes Care. 2009 ; Bind 32, Nr. 6. s. 1046-8.

Bibtex

@article{ea05b9e067f011df928f000ea68e967b,
title = "Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes",
abstract = "OBJECTIVE: To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality). RESEARCH DESIGN AND METHODS: Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes. RESULTS: The risk of serious adverse outcome at different A1C levels was compared with the background population. The risk was significantly higher when peri-conceptional A1C exceeded 6.9%, and the risk tended to increase gradually with increasing A1C. Women with A1C exceeding 10.4% had a very high risk of 16%. Congenital malformation rate increased significantly at A1C above 10.4%, whereas perinatal mortality was increased even at A1C below 6.9%. CONCLUSIONS: These results support recent guidelines of preconceptional A1C levels <7% in women with type 1 diabetes.",
author = "Jensen, {Dorte M} and Lars Korsholm and Per Ovesen and Henning Beck-Nielsen and Lars Moelsted-Pedersen and Westergaard, {Jes G} and Margrethe Moeller and Peter Damm and Dorte Jensen and Lauridsen, {Lars Korsholm} and Ovesen, {Per Glud} and Henning Beck-Nielsen and Lars Moelsted-Pedersen and Westergaard, {Jes G} and Margrethe Moeller and Peter Damm",
note = "Keywords: Body Mass Index; Chromosome Aberrations; Diabetes Mellitus, Type 1; European Continental Ancestry Group; Female; Hemoglobin A, Glycosylated; Humans; Infant, Newborn; Perinatal Mortality; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Retrospective Studies",
year = "2009",
month = jun,
day = "1",
doi = "10.2337/dc08-2061",
language = "English",
volume = "32",
pages = "1046--8",
journal = "Diabetes Care",
issn = "0149-5992",
publisher = "American Diabetes Association",
number = "6",

}

RIS

TY - JOUR

T1 - Peri-conceptional A1C and risk of serious adverse pregnancy outcome in 933 women with type 1 diabetes

AU - Jensen, Dorte M

AU - Korsholm, Lars

AU - Ovesen, Per

AU - Beck-Nielsen, Henning

AU - Moelsted-Pedersen, Lars

AU - Westergaard, Jes G

AU - Moeller, Margrethe

AU - Damm, Peter

AU - Jensen, Dorte

AU - Lauridsen, Lars Korsholm

AU - Ovesen, Per Glud

AU - Beck-Nielsen, Henning

AU - Moelsted-Pedersen, Lars

AU - Westergaard, Jes G

AU - Moeller, Margrethe

AU - Damm, Peter

N1 - Keywords: Body Mass Index; Chromosome Aberrations; Diabetes Mellitus, Type 1; European Continental Ancestry Group; Female; Hemoglobin A, Glycosylated; Humans; Infant, Newborn; Perinatal Mortality; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Prospective Studies; Retrospective Studies

PY - 2009/6/1

Y1 - 2009/6/1

N2 - OBJECTIVE: To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality). RESEARCH DESIGN AND METHODS: Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes. RESULTS: The risk of serious adverse outcome at different A1C levels was compared with the background population. The risk was significantly higher when peri-conceptional A1C exceeded 6.9%, and the risk tended to increase gradually with increasing A1C. Women with A1C exceeding 10.4% had a very high risk of 16%. Congenital malformation rate increased significantly at A1C above 10.4%, whereas perinatal mortality was increased even at A1C below 6.9%. CONCLUSIONS: These results support recent guidelines of preconceptional A1C levels <7% in women with type 1 diabetes.

AB - OBJECTIVE: To study the association between peri-conceptional A1C and serious adverse pregnancy outcome (congenital malformations and perinatal mortality). RESEARCH DESIGN AND METHODS: Prospective data were collected in 933 singleton pregnancies complicated by type 1 diabetes. RESULTS: The risk of serious adverse outcome at different A1C levels was compared with the background population. The risk was significantly higher when peri-conceptional A1C exceeded 6.9%, and the risk tended to increase gradually with increasing A1C. Women with A1C exceeding 10.4% had a very high risk of 16%. Congenital malformation rate increased significantly at A1C above 10.4%, whereas perinatal mortality was increased even at A1C below 6.9%. CONCLUSIONS: These results support recent guidelines of preconceptional A1C levels <7% in women with type 1 diabetes.

U2 - 10.2337/dc08-2061

DO - 10.2337/dc08-2061

M3 - Journal article

C2 - 19265024

VL - 32

SP - 1046

EP - 1048

JO - Diabetes Care

JF - Diabetes Care

SN - 0149-5992

IS - 6

ER -

ID: 19953858