Perfusion imaging using rubidium-82 ((82)Rb) PET in rats with myocardial infarction: First small animal cardiac (82)Rb-PET
Publikation: Bidrag til tidsskrift › Letter › Forskning › fagfællebedømt
Dokumenter
- Perfusion imaging using rubidium-82 (82Rb) PET in rats with myocardial infarction: First small animal cardiac 82Rb-PET
Forlagets udgivne version, 751 KB, PDF-dokument
Assessing myocardial perfusion using 82Rb-PET is emerging as a valuable clinical tool.1,2 The rapid decay (T½ = 76 s) allows for absolute quantification of both rest and stress perfusion within 30 minutes. In addition to evaluation of epicardial disease with perfusion defects, also evaluation of balanced coronary and small vessel disease is possible. For further evaluation of how 82Rb-PET can be used clinically, pre-clinical application of the method would be valuable. However, so far no data on the use of 82Rb-PET in small animals have been published nor has the use of 82Rb-PET, to the best of our knowledge, been successfully tried. Therefore, we wanted to develop and test the applicability of the method in rats, despite the high positron range of 82Rb. To do so, we adapted the clinical method and tested it in rats with experimentally induced myocardial infarction.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Journal of Nuclear Cardiology |
Vol/bind | 24 |
Udgave nummer | 2 |
Sider (fra-til) | 750-752 |
Antal sider | 3 |
ISSN | 1071-3581 |
DOI | |
Status | Udgivet - feb. 2017 |
Antal downloads er baseret på statistik fra Google Scholar og www.ku.dk
Ingen data tilgængelig
ID: 174693730