Pediatric reference intervals for general clinical chemistry components: merging of studies from Denmark and Sweden
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Pediatric reference intervals for general clinical chemistry components : merging of studies from Denmark and Sweden. / Ridefelt, Peter; Hilsted, Linda; Juul, Anders; Hellberg, Dan; Rustad, Pål.
I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 78, Nr. 5, 2018, s. 365-372.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Pediatric reference intervals for general clinical chemistry components
T2 - merging of studies from Denmark and Sweden
AU - Ridefelt, Peter
AU - Hilsted, Linda
AU - Juul, Anders
AU - Hellberg, Dan
AU - Rustad, Pål
PY - 2018
Y1 - 2018
N2 - BACKGROUND: Reference intervals are crucial tools aiding clinicians when making medical decisions. However, for children such values often are lacking or incomplete. The present study combines data from separate pediatric reference interval studies of Denmark and Sweden in order to increase sample size and to include also pre-school children who were lacking in the Danish study.METHODS: Results from two separate studies including 1988 healthy children and adolescents aged 6 months to 18 years of age were merged and recalculated. Eighteen general clinical chemistry components were measured on Abbott and Roche platforms. To facilitate commutability, the NFKK Reference Serum X was used.RESULTS: Age- and gender-specific pediatric reference intervals were defined by calculating 2.5 and 97.5 percentiles.CONCLUSION: The data generated are primarily applicable to a Nordic population, but could be used by any laboratory if validated for the local patient population.
AB - BACKGROUND: Reference intervals are crucial tools aiding clinicians when making medical decisions. However, for children such values often are lacking or incomplete. The present study combines data from separate pediatric reference interval studies of Denmark and Sweden in order to increase sample size and to include also pre-school children who were lacking in the Danish study.METHODS: Results from two separate studies including 1988 healthy children and adolescents aged 6 months to 18 years of age were merged and recalculated. Eighteen general clinical chemistry components were measured on Abbott and Roche platforms. To facilitate commutability, the NFKK Reference Serum X was used.RESULTS: Age- and gender-specific pediatric reference intervals were defined by calculating 2.5 and 97.5 percentiles.CONCLUSION: The data generated are primarily applicable to a Nordic population, but could be used by any laboratory if validated for the local patient population.
KW - Adolescent
KW - Age Factors
KW - Biomarkers/blood
KW - Child
KW - Child, Preschool
KW - Clinical Chemistry Tests/standards
KW - Denmark
KW - Female
KW - Humans
KW - Infant
KW - Male
KW - Reference Values
KW - Sex Factors
KW - Sweden
U2 - 10.1080/00365513.2018.1474493
DO - 10.1080/00365513.2018.1474493
M3 - Journal article
C2 - 29806781
VL - 78
SP - 365
EP - 372
JO - Scandinavian Journal of Clinical & Laboratory Investigation
JF - Scandinavian Journal of Clinical & Laboratory Investigation
SN - 0036-5513
IS - 5
ER -
ID: 217662779