Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function.
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The relation between pancreatic tissue fluid pressure and pain, morphology, and function was studied in a cross-sectional investigation. Pressure measurements were performed by percutaneous fine-needle puncture. Thirty-nine patients with chronic pancreatitis were included, 25 with pain and 14 without pain. The pressure was higher in patients with pain than in patients without pain (p = 0.000001), and this was significantly related to a pain score from a visual analogue scale (p less than 0.001). Patients with pancreatic pseudocysts had both higher pressure and higher pain score than patients without (p = 0.004 and p = 0.0003, respectively). The pressure was significantly related (inversely) to pancreatic duct diameter only in the group of 19 patients with earlier pancreatic surgery (R = -0.57, p = 0.02). The pressure was not related to functional factors or the presence of pancreatic calcifications. In conclusion, pancreatic tissue fluid pressure is a valuable indicator of pain in chronic pancreatitis.
Bidragets oversatte titel | Pancreatic tissue fluid pressure in chronic pancreatitis. Relation to pain, morphology, and function. |
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Originalsprog | Engelsk |
Tidsskrift | Scandinavian Journal of Gastroenterology |
Vol/bind | 25 |
Udgave nummer | 10 |
Sider (fra-til) | 1046-1051 |
Antal sider | 6 |
ISSN | 0036-5521 |
Status | Udgivet - 1990 |
ID: 34189350