Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites

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Standard

Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites. / Henriksen, Jens Henrik Sahl; Brøchner-Mortensen, J; Malchow-Møller, A; Schlichting, P.

I: Scandinavian Journal of Clinical & Laboratory Investigation, Bind 40, Nr. 3, 1980, s. 279-84.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Henriksen, JHS, Brøchner-Mortensen, J, Malchow-Møller, A & Schlichting, P 1980, 'Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites', Scandinavian Journal of Clinical & Laboratory Investigation, bind 40, nr. 3, s. 279-84.

APA

Henriksen, J. H. S., Brøchner-Mortensen, J., Malchow-Møller, A., & Schlichting, P. (1980). Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites. Scandinavian Journal of Clinical & Laboratory Investigation, 40(3), 279-84.

Vancouver

Henriksen JHS, Brøchner-Mortensen J, Malchow-Møller A, Schlichting P. Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites. Scandinavian Journal of Clinical & Laboratory Investigation. 1980;40(3):279-84.

Author

Henriksen, Jens Henrik Sahl ; Brøchner-Mortensen, J ; Malchow-Møller, A ; Schlichting, P. / Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites. I: Scandinavian Journal of Clinical & Laboratory Investigation. 1980 ; Bind 40, Nr. 3. s. 279-84.

Bibtex

@article{cbf780d04e1111df928f000ea68e967b,
title = "Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites",
abstract = "The total plasma (Clt) and the renal plasma (Clr) clearances of [51Cr]EDTA were determined simultaneously in nine patients with ascites due to liver cirrhosis. Clt (mean 78 ml/min, range 34-115 ml/min) was significantly higher than Clr (mean 52 ml/min, range 13-96 ml/min, P < 0.005). The ascitic fluid-plasma activity ratio of [51Cr]EDTA increased throughout the investigation period (5h). The results suggest that [51Cr]EDTA equilibrates slowly with the peritoneal space which indicates that Clt will over-estimate the glomerular filtration rate by approximately 20 ml/min in patients with ascites. To assess glomerular filtration rate in presence of ascites, the renal plasma clearance of [51Cr]EDTA should be used instead of the total plasma clearance.",
author = "Henriksen, {Jens Henrik Sahl} and J Br{\o}chner-Mortensen and A Malchow-M{\o}ller and P Schlichting",
note = "Keywords: Adult; Age Factors; Ascites; Body Weight; Chromium Radioisotopes; Creatinine; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Kidney; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Sex Factors",
year = "1980",
language = "English",
volume = "40",
pages = "279--84",
journal = "Scandinavian Journal of Clinical & Laboratory Investigation",
issn = "0036-5513",
publisher = "Taylor & Francis",
number = "3",

}

RIS

TY - JOUR

T1 - Over-estimation of glomerular filtration rate by single injection [51Cr]EDTA plasma clearance determination in patients with ascites

AU - Henriksen, Jens Henrik Sahl

AU - Brøchner-Mortensen, J

AU - Malchow-Møller, A

AU - Schlichting, P

N1 - Keywords: Adult; Age Factors; Ascites; Body Weight; Chromium Radioisotopes; Creatinine; Edetic Acid; Female; Glomerular Filtration Rate; Humans; Kidney; Liver Cirrhosis; Male; Metabolic Clearance Rate; Middle Aged; Sex Factors

PY - 1980

Y1 - 1980

N2 - The total plasma (Clt) and the renal plasma (Clr) clearances of [51Cr]EDTA were determined simultaneously in nine patients with ascites due to liver cirrhosis. Clt (mean 78 ml/min, range 34-115 ml/min) was significantly higher than Clr (mean 52 ml/min, range 13-96 ml/min, P < 0.005). The ascitic fluid-plasma activity ratio of [51Cr]EDTA increased throughout the investigation period (5h). The results suggest that [51Cr]EDTA equilibrates slowly with the peritoneal space which indicates that Clt will over-estimate the glomerular filtration rate by approximately 20 ml/min in patients with ascites. To assess glomerular filtration rate in presence of ascites, the renal plasma clearance of [51Cr]EDTA should be used instead of the total plasma clearance.

AB - The total plasma (Clt) and the renal plasma (Clr) clearances of [51Cr]EDTA were determined simultaneously in nine patients with ascites due to liver cirrhosis. Clt (mean 78 ml/min, range 34-115 ml/min) was significantly higher than Clr (mean 52 ml/min, range 13-96 ml/min, P < 0.005). The ascitic fluid-plasma activity ratio of [51Cr]EDTA increased throughout the investigation period (5h). The results suggest that [51Cr]EDTA equilibrates slowly with the peritoneal space which indicates that Clt will over-estimate the glomerular filtration rate by approximately 20 ml/min in patients with ascites. To assess glomerular filtration rate in presence of ascites, the renal plasma clearance of [51Cr]EDTA should be used instead of the total plasma clearance.

M3 - Journal article

C2 - 6777855

VL - 40

SP - 279

EP - 284

JO - Scandinavian Journal of Clinical & Laboratory Investigation

JF - Scandinavian Journal of Clinical & Laboratory Investigation

SN - 0036-5513

IS - 3

ER -

ID: 19398521