Optics miniaturization strategy for demanding Raman spectroscopy applications

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

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Optics miniaturization strategy for demanding Raman spectroscopy applications. / Ilchenko, Oleksii; Pilhun, Yurii; Kutsyk, Andrii; Slobodianiuk, Denys; Goksel, Yaman; Dumont, Elodie; Vaut, Lukas; Mazzoni, Chiara; Morelli, Lidia; Boisen, Sofus; Stergiou, Konstantinos; Aulin, Yaroslav; Rindzevicius, Tomas; Andersen, Thomas Emil; Lassen, Mikael; Mundhada, Hemanshu; Jendresen, Christian Bille; Philipsen, Peter Alshede; Hædersdal, Merete; Boisen, Anja.

I: Nature Communications, Bind 15, Nr. 1, 3049, 2024.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Ilchenko, O, Pilhun, Y, Kutsyk, A, Slobodianiuk, D, Goksel, Y, Dumont, E, Vaut, L, Mazzoni, C, Morelli, L, Boisen, S, Stergiou, K, Aulin, Y, Rindzevicius, T, Andersen, TE, Lassen, M, Mundhada, H, Jendresen, CB, Philipsen, PA, Hædersdal, M & Boisen, A 2024, 'Optics miniaturization strategy for demanding Raman spectroscopy applications', Nature Communications, bind 15, nr. 1, 3049. https://doi.org/10.1038/s41467-024-47044-7

APA

Ilchenko, O., Pilhun, Y., Kutsyk, A., Slobodianiuk, D., Goksel, Y., Dumont, E., Vaut, L., Mazzoni, C., Morelli, L., Boisen, S., Stergiou, K., Aulin, Y., Rindzevicius, T., Andersen, T. E., Lassen, M., Mundhada, H., Jendresen, C. B., Philipsen, P. A., Hædersdal, M., & Boisen, A. (2024). Optics miniaturization strategy for demanding Raman spectroscopy applications. Nature Communications, 15(1), [3049]. https://doi.org/10.1038/s41467-024-47044-7

Vancouver

Ilchenko O, Pilhun Y, Kutsyk A, Slobodianiuk D, Goksel Y, Dumont E o.a. Optics miniaturization strategy for demanding Raman spectroscopy applications. Nature Communications. 2024;15(1). 3049. https://doi.org/10.1038/s41467-024-47044-7

Author

Ilchenko, Oleksii ; Pilhun, Yurii ; Kutsyk, Andrii ; Slobodianiuk, Denys ; Goksel, Yaman ; Dumont, Elodie ; Vaut, Lukas ; Mazzoni, Chiara ; Morelli, Lidia ; Boisen, Sofus ; Stergiou, Konstantinos ; Aulin, Yaroslav ; Rindzevicius, Tomas ; Andersen, Thomas Emil ; Lassen, Mikael ; Mundhada, Hemanshu ; Jendresen, Christian Bille ; Philipsen, Peter Alshede ; Hædersdal, Merete ; Boisen, Anja. / Optics miniaturization strategy for demanding Raman spectroscopy applications. I: Nature Communications. 2024 ; Bind 15, Nr. 1.

Bibtex

@article{a26a613d70984404a746a7e26a338c69,

title = "Optics miniaturization strategy for demanding Raman spectroscopy applications",

abstract = "Raman spectroscopy provides non-destructive, label-free quantitative studies of chemical compositions at the microscale as used on NASA's Perseverance rover on Mars. Such capabilities come at the cost of high requirements for instrumentation. Here we present a centimeter-scale miniaturization of a Raman spectrometer using cheap non-stabilized laser diodes, densely packed optics, and non-cooled small sensors. The performance is comparable with expensive bulky research-grade Raman systems. It has excellent sensitivity, low power consumption, perfect wavenumber, intensity calibration, and 7 cm-1 resolution within the 400-4000 cm-1 range using a built-in reference. High performance and versatility are demonstrated in use cases including quantification of methanol in beverages, in-vivo Raman measurements of human skin, fermentation monitoring, chemical Raman mapping at sub-micrometer resolution, quantitative SERS mapping of the anti-cancer drug methotrexate and in-vitro bacteria identification. We foresee that the miniaturization will allow realization of super-compact Raman spectrometers for integration in smartphones and medical devices, democratizing Raman technology.",

author = "Oleksii Ilchenko and Yurii Pilhun and Andrii Kutsyk and Denys Slobodianiuk and Yaman Goksel and Elodie Dumont and Lukas Vaut and Chiara Mazzoni and Lidia Morelli and Sofus Boisen and Konstantinos Stergiou and Yaroslav Aulin and Tomas Rindzevicius and Andersen, {Thomas Emil} and Mikael Lassen and Hemanshu Mundhada and Jendresen, {Christian Bille} and Philipsen, {Peter Alshede} and Merete H{\ae}dersdal and Anja Boisen",

note = "Publisher Copyright: {\textcopyright} 2024. The Author(s).",

year = "2024",

doi = "10.1038/s41467-024-47044-7",

language = "English",

volume = "15",

journal = "Nature Communications",

issn = "2041-1723",

publisher = "nature publishing group",

number = "1",

}

RIS

TY - JOUR

T1 - Optics miniaturization strategy for demanding Raman spectroscopy applications

AU - Ilchenko, Oleksii

AU - Pilhun, Yurii

AU - Kutsyk, Andrii

AU - Slobodianiuk, Denys

AU - Goksel, Yaman

AU - Dumont, Elodie

AU - Vaut, Lukas

AU - Mazzoni, Chiara

AU - Morelli, Lidia

AU - Boisen, Sofus

AU - Stergiou, Konstantinos

AU - Aulin, Yaroslav

AU - Rindzevicius, Tomas

AU - Andersen, Thomas Emil

AU - Lassen, Mikael

AU - Mundhada, Hemanshu

AU - Jendresen, Christian Bille

AU - Philipsen, Peter Alshede

AU - Hædersdal, Merete

AU - Boisen, Anja

PY - 2024

Y1 - 2024

N2 - Raman spectroscopy provides non-destructive, label-free quantitative studies of chemical compositions at the microscale as used on NASA's Perseverance rover on Mars. Such capabilities come at the cost of high requirements for instrumentation. Here we present a centimeter-scale miniaturization of a Raman spectrometer using cheap non-stabilized laser diodes, densely packed optics, and non-cooled small sensors. The performance is comparable with expensive bulky research-grade Raman systems. It has excellent sensitivity, low power consumption, perfect wavenumber, intensity calibration, and 7 cm-1 resolution within the 400-4000 cm-1 range using a built-in reference. High performance and versatility are demonstrated in use cases including quantification of methanol in beverages, in-vivo Raman measurements of human skin, fermentation monitoring, chemical Raman mapping at sub-micrometer resolution, quantitative SERS mapping of the anti-cancer drug methotrexate and in-vitro bacteria identification. We foresee that the miniaturization will allow realization of super-compact Raman spectrometers for integration in smartphones and medical devices, democratizing Raman technology.

AB - Raman spectroscopy provides non-destructive, label-free quantitative studies of chemical compositions at the microscale as used on NASA's Perseverance rover on Mars. Such capabilities come at the cost of high requirements for instrumentation. Here we present a centimeter-scale miniaturization of a Raman spectrometer using cheap non-stabilized laser diodes, densely packed optics, and non-cooled small sensors. The performance is comparable with expensive bulky research-grade Raman systems. It has excellent sensitivity, low power consumption, perfect wavenumber, intensity calibration, and 7 cm-1 resolution within the 400-4000 cm-1 range using a built-in reference. High performance and versatility are demonstrated in use cases including quantification of methanol in beverages, in-vivo Raman measurements of human skin, fermentation monitoring, chemical Raman mapping at sub-micrometer resolution, quantitative SERS mapping of the anti-cancer drug methotrexate and in-vitro bacteria identification. We foresee that the miniaturization will allow realization of super-compact Raman spectrometers for integration in smartphones and medical devices, democratizing Raman technology.

U2 - 10.1038/s41467-024-47044-7

DO - 10.1038/s41467-024-47044-7

M3 - Journal article

C2 - 38589380

AN - SCOPUS:85190351831

VL - 15

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 3049

ER -

ID: 389546758