NT-proBNP levels, atherosclerosis and vascular function in asymptomatic type 2 diabetic patients with microalbuminuria: peripheral reactive hyperaemia index but not NT-proBNP is an independent predictor of coronary atherosclerosis
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NT-proBNP levels, atherosclerosis and vascular function in asymptomatic type 2 diabetic patients with microalbuminuria: peripheral reactive hyperaemia index but not NT-proBNP is an independent predictor of coronary atherosclerosis. / Reinhard, Henrik; Wiinberg, Niels; Hansen, Peter R; Kjær, Andreas; Petersen, Claus L; Winther, Kaj; Parving, Hans-Henrik; Rossing, Peter; Jacobsen, Peter.
I: Cardiovascular Diabetology, Bind 10, 2011, s. 71.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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T1 - NT-proBNP levels, atherosclerosis and vascular function in asymptomatic type 2 diabetic patients with microalbuminuria: peripheral reactive hyperaemia index but not NT-proBNP is an independent predictor of coronary atherosclerosis
AU - Reinhard, Henrik
AU - Wiinberg, Niels
AU - Hansen, Peter R
AU - Kjær, Andreas
AU - Petersen, Claus L
AU - Winther, Kaj
AU - Parving, Hans-Henrik
AU - Rossing, Peter
AU - Jacobsen, Peter
PY - 2011
Y1 - 2011
N2 - Intensive multifactorial treatment aimed at cardiovascular (CV) risk factor reduction in type 2 diabetic patients with microalbuminuria can diminish fatal and non-fatal CV. Plasma N-terminal (NT)-proBNP predicts CV mortality in diabetic patients but the utility of P-NT-proBNP in screening for atherosclerosis is unclear. We examined the interrelationship between P-NT-proBNP, presence of atherosclerosis and/or vascular dysfunction in the coronary, carotid and peripheral arteries in asymptomatic type 2 diabetic patients with microalbuminuria that received intensive multifactorial treatment. METHODS AND RESULTS: P-NT-proBNP was measured in 200 asymptomatic type 2 patients without known cardiac disease that received intensive multifactorial treatment for CV risk reduction. Patients were examined for coronary, carotid and peripheral atherosclerosis, as defined by coronary calcium score=400, carotid intima-media thickness (CIMT)>0.90 mm, ankle-brachial index
AB - Intensive multifactorial treatment aimed at cardiovascular (CV) risk factor reduction in type 2 diabetic patients with microalbuminuria can diminish fatal and non-fatal CV. Plasma N-terminal (NT)-proBNP predicts CV mortality in diabetic patients but the utility of P-NT-proBNP in screening for atherosclerosis is unclear. We examined the interrelationship between P-NT-proBNP, presence of atherosclerosis and/or vascular dysfunction in the coronary, carotid and peripheral arteries in asymptomatic type 2 diabetic patients with microalbuminuria that received intensive multifactorial treatment. METHODS AND RESULTS: P-NT-proBNP was measured in 200 asymptomatic type 2 patients without known cardiac disease that received intensive multifactorial treatment for CV risk reduction. Patients were examined for coronary, carotid and peripheral atherosclerosis, as defined by coronary calcium score=400, carotid intima-media thickness (CIMT)>0.90 mm, ankle-brachial index
U2 - http://dx.doi.org/10.1186/1475-2840-10-71
DO - http://dx.doi.org/10.1186/1475-2840-10-71
M3 - Journal article
VL - 10
SP - 71
JO - Cardiovascular Diabetology
JF - Cardiovascular Diabetology
SN - 1475-2840
ER -
ID: 40158630