Non-specific esterases and esterproteases in masticatory muscles from the muscular dystrophic mouse
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Non-specific esterases and esterproteases in masticatory muscles from the muscular dystrophic mouse. / Kirkeby, S; Moe, D; Vilmann, H.
I: Neurochemical Research, Bind 14, Nr. 3, 1989, s. 211-5.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Non-specific esterases and esterproteases in masticatory muscles from the muscular dystrophic mouse
AU - Kirkeby, S
AU - Moe, D
AU - Vilmann, H
N1 - Keywords: Animals; Esterases; Esters; Masticatory Muscles; Mice; Mice, Inbred C57BL; Muscular Dystrophy, Animal; Peptide Hydrolases
PY - 1989
Y1 - 1989
N2 - With the aid of histochemical and electrophoretic techniques activities for esterase and esterprotease were investigated in the digastric and masseter muscles from normal and dystrophic mice. The substrates used were alpha-naphthyl acetate and N-acetyl-L-alanine alpha-naphthyl ester. According to the microscopic observations of the dystrophic muscles the histopathological changes in the masseter muscle were much more pronounced than in the digastric muscle. The connective tissue surrounding the myofibers of the dystrophic masseter contained a large number of cells with pronounced enzyme activity. Among them were mast cells that were strongly stained for esterprotease. The connective tissue of the dystrophic digastricus was much less infiltrated with cellular elements reacting for esterprotease. In zymograms the normal digastricus, the dystrophic masseter and the dystrophic digastricus showed a strong activity for certain isoenzymes that were absent or weakly expressed in the normal masseter.
AB - With the aid of histochemical and electrophoretic techniques activities for esterase and esterprotease were investigated in the digastric and masseter muscles from normal and dystrophic mice. The substrates used were alpha-naphthyl acetate and N-acetyl-L-alanine alpha-naphthyl ester. According to the microscopic observations of the dystrophic muscles the histopathological changes in the masseter muscle were much more pronounced than in the digastric muscle. The connective tissue surrounding the myofibers of the dystrophic masseter contained a large number of cells with pronounced enzyme activity. Among them were mast cells that were strongly stained for esterprotease. The connective tissue of the dystrophic digastricus was much less infiltrated with cellular elements reacting for esterprotease. In zymograms the normal digastricus, the dystrophic masseter and the dystrophic digastricus showed a strong activity for certain isoenzymes that were absent or weakly expressed in the normal masseter.
M3 - Journal article
C2 - 2657470
VL - 14
SP - 211
EP - 215
JO - Neurochemical Research
JF - Neurochemical Research
SN - 0364-3190
IS - 3
ER -
ID: 10141262