Methylphenidate misuse in adult patients and the impact of therapeutic use

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Methylphenidate misuse in adult patients and the impact of therapeutic use. / Jensen, L S; Pagsberg, Anne Katrine; Dalhoff, Kim.

I: Human & Experimental Toxicology, Bind 34, Nr. 5, 2015, s. 460-467.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Jensen, LS, Pagsberg, AK & Dalhoff, K 2015, 'Methylphenidate misuse in adult patients and the impact of therapeutic use', Human & Experimental Toxicology, bind 34, nr. 5, s. 460-467. https://doi.org/10.1177/0960327114543935

APA

Jensen, L. S., Pagsberg, A. K., & Dalhoff, K. (2015). Methylphenidate misuse in adult patients and the impact of therapeutic use. Human & Experimental Toxicology, 34(5), 460-467. https://doi.org/10.1177/0960327114543935

Vancouver

Jensen LS, Pagsberg AK, Dalhoff K. Methylphenidate misuse in adult patients and the impact of therapeutic use. Human & Experimental Toxicology. 2015;34(5):460-467. https://doi.org/10.1177/0960327114543935

Author

Jensen, L S ; Pagsberg, Anne Katrine ; Dalhoff, Kim. / Methylphenidate misuse in adult patients and the impact of therapeutic use. I: Human & Experimental Toxicology. 2015 ; Bind 34, Nr. 5. s. 460-467.

Bibtex

@article{21681d58dd8647e29d7705413b5d8a6c,
title = "Methylphenidate misuse in adult patients and the impact of therapeutic use",
abstract = "OBJECTIVE: Methylphenidate (MPH) prescription rates for adults increase, but the extent of a parallel rise in toxic exposures and their causes and distribution between different MPH trade names are unexplored.METHOD: We retrospectively analyzed adult MPH exposures reported to the Danish Poison Information Centre from January 2006 to July 2012 and the association with MPH sales and the number of patients prescribed MPH.RESULTS: Of the 394 exposures (57% males, median age 27 years) reported, MPH status was available in 249 of whom 65.5% were prescribed MPH. Exposure was in 54% motivated by suicidal attempt and in 40% by recreational use (based on 375 cases). Exposure was dominated by one trade name and exposure incidence correlated significantly with sales ( p = 0.001) and prevalence of MPH-treated patients ( p = 0.0008).CONCLUSIONS: The increase in MPH exposures parallels the prescription rates (particularly Ritalin({\textregistered})/Ritalin({\textregistered}) Uno). Most exposures were intentional and motivated by suicide attempts or recreational use.",
author = "Jensen, {L S} and Pagsberg, {Anne Katrine} and Kim Dalhoff",
note = "{\textcopyright} The Author(s) 2014.",
year = "2015",
doi = "10.1177/0960327114543935",
language = "English",
volume = "34",
pages = "460--467",
journal = "Human and Experimental Toxicology",
issn = "0960-3271",
publisher = "SAGE Publications",
number = "5",

}

RIS

TY - JOUR

T1 - Methylphenidate misuse in adult patients and the impact of therapeutic use

AU - Jensen, L S

AU - Pagsberg, Anne Katrine

AU - Dalhoff, Kim

N1 - © The Author(s) 2014.

PY - 2015

Y1 - 2015

N2 - OBJECTIVE: Methylphenidate (MPH) prescription rates for adults increase, but the extent of a parallel rise in toxic exposures and their causes and distribution between different MPH trade names are unexplored.METHOD: We retrospectively analyzed adult MPH exposures reported to the Danish Poison Information Centre from January 2006 to July 2012 and the association with MPH sales and the number of patients prescribed MPH.RESULTS: Of the 394 exposures (57% males, median age 27 years) reported, MPH status was available in 249 of whom 65.5% were prescribed MPH. Exposure was in 54% motivated by suicidal attempt and in 40% by recreational use (based on 375 cases). Exposure was dominated by one trade name and exposure incidence correlated significantly with sales ( p = 0.001) and prevalence of MPH-treated patients ( p = 0.0008).CONCLUSIONS: The increase in MPH exposures parallels the prescription rates (particularly Ritalin(®)/Ritalin(®) Uno). Most exposures were intentional and motivated by suicide attempts or recreational use.

AB - OBJECTIVE: Methylphenidate (MPH) prescription rates for adults increase, but the extent of a parallel rise in toxic exposures and their causes and distribution between different MPH trade names are unexplored.METHOD: We retrospectively analyzed adult MPH exposures reported to the Danish Poison Information Centre from January 2006 to July 2012 and the association with MPH sales and the number of patients prescribed MPH.RESULTS: Of the 394 exposures (57% males, median age 27 years) reported, MPH status was available in 249 of whom 65.5% were prescribed MPH. Exposure was in 54% motivated by suicidal attempt and in 40% by recreational use (based on 375 cases). Exposure was dominated by one trade name and exposure incidence correlated significantly with sales ( p = 0.001) and prevalence of MPH-treated patients ( p = 0.0008).CONCLUSIONS: The increase in MPH exposures parallels the prescription rates (particularly Ritalin(®)/Ritalin(®) Uno). Most exposures were intentional and motivated by suicide attempts or recreational use.

U2 - 10.1177/0960327114543935

DO - 10.1177/0960327114543935

M3 - Journal article

C2 - 25062974

VL - 34

SP - 460

EP - 467

JO - Human and Experimental Toxicology

JF - Human and Experimental Toxicology

SN - 0960-3271

IS - 5

ER -

ID: 137746815