Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney

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Standard

Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. / Toft, B.S.; Hansen, Harald S.

I: B B A - Molecular and Cell Biology of Lipids, Bind 574, Nr. 1, 27.07.1979, s. 33-38.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Toft, BS & Hansen, HS 1979, 'Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney', B B A - Molecular and Cell Biology of Lipids, bind 574, nr. 1, s. 33-38.

APA

Toft, B. S., & Hansen, H. S. (1979). Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. B B A - Molecular and Cell Biology of Lipids, 574(1), 33-38.

Vancouver

Toft BS, Hansen HS. Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. B B A - Molecular and Cell Biology of Lipids. 1979 jul. 27;574(1):33-38.

Author

Toft, B.S. ; Hansen, Harald S. / Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney. I: B B A - Molecular and Cell Biology of Lipids. 1979 ; Bind 574, Nr. 1. s. 33-38.

Bibtex

@article{e3ce2a06e5dd434ea2e4e72d722a27ab,

title = "Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney",

abstract = "Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.",

author = "B.S. Toft and Hansen, {Harald S.}",

year = "1979",

month = jul,

day = "27",

language = "English",

volume = "574",

pages = "33--38",

journal = "B B A - Molecular and Cell Biology of Lipids",

issn = "1388-1981",

publisher = "Elsevier",

number = "1",

}

RIS

TY - JOUR

T1 - Metabolism of prostaglandin E and of glutathione conjugate of prostaglandin A (GSH-prostaglandin A) by prostaglandin 9-ketoreductase from rabbit kidney

AU - Toft, B.S.

AU - Hansen, Harald S.

PY - 1979/7/27

Y1 - 1979/7/27

N2 - Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.

AB - Rabbit kidney prostaglandin 9-ketoreductase was found to metabolize the glutathione conjugate of prostaglandin A (GSH-prostaglandin A). Apparent K (GSH-prostaglandin A) 13 µM and apparent K (prostaglandin E) 200 µM. The cytosolic preparation was subjected to gelfiltration and isoelectric focusing, which revealed that metabolism of prostaglandin E and GSH-prostaglandin A occurs by means of the same fractions. Furthermore, prostaglandin E and GSH-prostaglandin A are competitive inhibitors of the enzyme, when GSH-prostaglandin A and prostaglandin E are tested as substrates, respectively. It is concluded, that GSH-prostaglandin A is a much better substrate for prostaglandin 9-ketoreductase from rabbit kidney than is prostaglandin E.

UR - http://www.scopus.com/inward/record.url?scp=0018654510&partnerID=8YFLogxK

M3 - Journal article

AN - SCOPUS:0018654510

VL - 574

SP - 33

EP - 38

JO - B B A - Molecular and Cell Biology of Lipids

JF - B B A - Molecular and Cell Biology of Lipids

SN - 1388-1981

IS - 1

ER -

ID: 45562933