Massive haplotypes underlie ecotypic differentiation in sunflowers
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Species often include multiple ecotypes that are adapted to different environments1. However, it is unclear how ecotypes arise and how their distinctive combinations of adaptive alleles are maintained despite hybridization with non-adapted populations2–4. Here, by resequencing 1,506 wild sunflowers from 3 species (Helianthus annuus, Helianthus petiolaris and Helianthus argophyllus), we identify 37 large (1–100 Mbp in size), non-recombining haplotype blocks that are associated with numerous ecologically relevant traits, as well as soil and climate characteristics. Limited recombination in these haplotype blocks keeps adaptive alleles together, and these regions differentiate sunflower ecotypes. For example, haplotype blocks control a 77-day difference in flowering between ecotypes of the silverleaf sunflower H. argophyllus (probably through deletion of a homologue of FLOWERING LOCUS T (FT)), and are associated with seed size, flowering time and soil fertility in dune-adapted sunflowers. These haplotypes are highly divergent, frequently associated with structural variants and often appear to represent introgressions from other—possibly now-extinct—congeners. These results highlight a pervasive role of structural variation in ecotypic adaptation.
Originalsprog | Engelsk |
---|---|
Tidsskrift | Nature |
Vol/bind | 584 |
Udgave nummer | 7822 |
Sider (fra-til) | 602-607 |
Antal sider | 6 |
ISSN | 0028-0836 |
DOI | |
Status | Udgivet - 2020 |
Eksternt udgivet | Ja |
Bibliografisk note
Funding Information:
Acknowledgements We thank J. Gouzy and N. B. Langlade for providing access to the HA412-HOv2 annotation and PSC8 genome assembly; B. T. Moyers for discussion and providing the H. argophyllus picture; J. Lee-Yaw and A. J. Moreno-Geraldes for comments; D. Skonieczny, A. Kim, A. Parra and C. Konecny for assistance with fieldwork and data acquisition; A. Warfield for computing advice; J. D. Herndon for providing the dune H. petiolaris picture; D. G. Grimm for assistance with easyGWAS; UBC’s Data Science Institute for support to J.S.L.; and Compute Canada for computing resources. Maps were realized using tiles from Stamen Design (https://stamen.com), under CC BY 3.0, from data by OpenStreetMaps contributors (https://openstreetmap.org), under ODbL. Funding was provided by Genome Canada and Genome BC (LSARP2014-223SUN), the NSF Plant Genome Program (IOS-1444522), the International Consortium for Sunflower Genomic Resources, Sofiproteol, an HFSP long-term postdoctoral fellowship to M.T. (LT000780/2013) and a Banting postdoctoral fellowship to G.L.O.
Publisher Copyright:
© 2020, The Author(s), under exclusive licence to Springer Nature Limited.
ID: 336610678