Long-term prognostic significance of homocysteine in middle-aged and elderly

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Standard

Long-term prognostic significance of homocysteine in middle-aged and elderly. / Petersen, Julie Falkenberg; Larsen, Bjørn Strøjer; Sabbah, Muhammad; Nielsen, Olav Wendelboe; Kumarathurai, Preman; Sajadieh, Ahmad.

I: Biomarkers, Bind 21, Nr. 6, 2016, s. 490-6.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Petersen, JF, Larsen, BS, Sabbah, M, Nielsen, OW, Kumarathurai, P & Sajadieh, A 2016, 'Long-term prognostic significance of homocysteine in middle-aged and elderly', Biomarkers, bind 21, nr. 6, s. 490-6. https://doi.org/10.3109/1354750X.2016.1160288

APA

Petersen, J. F., Larsen, B. S., Sabbah, M., Nielsen, O. W., Kumarathurai, P., & Sajadieh, A. (2016). Long-term prognostic significance of homocysteine in middle-aged and elderly. Biomarkers, 21(6), 490-6. https://doi.org/10.3109/1354750X.2016.1160288

Vancouver

Petersen JF, Larsen BS, Sabbah M, Nielsen OW, Kumarathurai P, Sajadieh A. Long-term prognostic significance of homocysteine in middle-aged and elderly. Biomarkers. 2016;21(6):490-6. https://doi.org/10.3109/1354750X.2016.1160288

Author

Petersen, Julie Falkenberg ; Larsen, Bjørn Strøjer ; Sabbah, Muhammad ; Nielsen, Olav Wendelboe ; Kumarathurai, Preman ; Sajadieh, Ahmad. / Long-term prognostic significance of homocysteine in middle-aged and elderly. I: Biomarkers. 2016 ; Bind 21, Nr. 6. s. 490-6.

Bibtex

@article{8a9e36fd9d31471d96c174e5973f0dc6,
title = "Long-term prognostic significance of homocysteine in middle-aged and elderly",
abstract = "OBJECTIVE: We investigated the association among increased levels of plasma homocysteine (Hcy), all-cause mortality, and cardiovascular events.METHODS: Hcy was measured in 670 middle-aged and elderly subjects with no previous manifest cardiovascular disease. The follow-up period was 15 years.RESULTS: Subjects with Hcy ≥ 10.8 μmol/l (n = 231) had a significant higher incidence of all-cause mortality (p < 0.001) and CV events (p < 0.001) compared with subjects with Hcy < 10.8 μmol/l (n = 439). However, there was no association on high levels of Hcy and VTE events or stroke.CONCLUSION: Increased levels of Hcy are associated with all-cause mortality and CV events.",
keywords = "Aged, Biomarkers, Cardiovascular Diseases, Disease-Free Survival, Female, Follow-Up Studies, Homocysteine, Humans, Incidence, Kaplan-Meier Estimate, Male, Middle Aged, Prognosis, Proportional Hazards Models, Risk Factors, Journal Article",
author = "Petersen, {Julie Falkenberg} and Larsen, {Bj{\o}rn Str{\o}jer} and Muhammad Sabbah and Nielsen, {Olav Wendelboe} and Preman Kumarathurai and Ahmad Sajadieh",
year = "2016",
doi = "10.3109/1354750X.2016.1160288",
language = "English",
volume = "21",
pages = "490--6",
journal = "Biomarkers",
issn = "1354-750X",
publisher = "Taylor & Francis",
number = "6",

}

RIS

TY - JOUR

T1 - Long-term prognostic significance of homocysteine in middle-aged and elderly

AU - Petersen, Julie Falkenberg

AU - Larsen, Bjørn Strøjer

AU - Sabbah, Muhammad

AU - Nielsen, Olav Wendelboe

AU - Kumarathurai, Preman

AU - Sajadieh, Ahmad

PY - 2016

Y1 - 2016

N2 - OBJECTIVE: We investigated the association among increased levels of plasma homocysteine (Hcy), all-cause mortality, and cardiovascular events.METHODS: Hcy was measured in 670 middle-aged and elderly subjects with no previous manifest cardiovascular disease. The follow-up period was 15 years.RESULTS: Subjects with Hcy ≥ 10.8 μmol/l (n = 231) had a significant higher incidence of all-cause mortality (p < 0.001) and CV events (p < 0.001) compared with subjects with Hcy < 10.8 μmol/l (n = 439). However, there was no association on high levels of Hcy and VTE events or stroke.CONCLUSION: Increased levels of Hcy are associated with all-cause mortality and CV events.

AB - OBJECTIVE: We investigated the association among increased levels of plasma homocysteine (Hcy), all-cause mortality, and cardiovascular events.METHODS: Hcy was measured in 670 middle-aged and elderly subjects with no previous manifest cardiovascular disease. The follow-up period was 15 years.RESULTS: Subjects with Hcy ≥ 10.8 μmol/l (n = 231) had a significant higher incidence of all-cause mortality (p < 0.001) and CV events (p < 0.001) compared with subjects with Hcy < 10.8 μmol/l (n = 439). However, there was no association on high levels of Hcy and VTE events or stroke.CONCLUSION: Increased levels of Hcy are associated with all-cause mortality and CV events.

KW - Aged

KW - Biomarkers

KW - Cardiovascular Diseases

KW - Disease-Free Survival

KW - Female

KW - Follow-Up Studies

KW - Homocysteine

KW - Humans

KW - Incidence

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Proportional Hazards Models

KW - Risk Factors

KW - Journal Article

U2 - 10.3109/1354750X.2016.1160288

DO - 10.3109/1354750X.2016.1160288

M3 - Journal article

C2 - 27008914

VL - 21

SP - 490

EP - 496

JO - Biomarkers

JF - Biomarkers

SN - 1354-750X

IS - 6

ER -

ID: 180945775