Ischemic postconditioning: a clinical perspective

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Ischemic postconditioning: a clinical perspective. / Lønborg, Jacob ; Treiman, Marek; Engstrøm, Thomas.

I: Interventional Cardiology, Bind 2, Nr. 4, 08.2010, s. 579-589.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Lønborg, J, Treiman, M & Engstrøm, T 2010, 'Ischemic postconditioning: a clinical perspective', Interventional Cardiology, bind 2, nr. 4, s. 579-589.

APA

Lønborg, J., Treiman, M., & Engstrøm, T. (2010). Ischemic postconditioning: a clinical perspective. Interventional Cardiology, 2(4), 579-589.

Vancouver

Lønborg J, Treiman M, Engstrøm T. Ischemic postconditioning: a clinical perspective. Interventional Cardiology. 2010 aug.;2(4):579-589.

Author

Lønborg, Jacob ; Treiman, Marek ; Engstrøm, Thomas. / Ischemic postconditioning: a clinical perspective. I: Interventional Cardiology. 2010 ; Bind 2, Nr. 4. s. 579-589.

Bibtex

@article{0f303f2a94574d1a95b058438833cb80,
title = "Ischemic postconditioning: a clinical perspective",
abstract = "Primary percutaneous coronary intervention is the recommended therapy for patients with STelevation myocardial infarction. However, restoration of coronary blood flow may lead to reperfusion injury, which has been suggested to account for 50% of the final myocardial infarct size. As an adjuvant therapy to primary percutaneous coronary intervention, ischemic postconditioning (IPost) has been shown to be safe and to underlie cardioprotection in several clinical trials. However, there remain important issues to be settled before IPost can be used routinely in patients undergoing primary percutaneous coronary intervention: first, determining which IPost protocol is the most optimal in humans; second, determining the effect of IPost on clinical outcome; third, determining in which patients should IPost be applied; and fourth, determining the effect on left ventricular function. This article discusses these issues with a clinical perspective and looks into alternative pharmacological cardioprotection. ",
author = "Jacob L{\o}nborg and Marek Treiman and Thomas Engstr{\o}m",
year = "2010",
month = aug,
language = "English",
volume = "2",
pages = "579--589",
journal = "Interventional Cardiology",
issn = "0926-9649",
publisher = "Springer",
number = "4",

}

RIS

TY - JOUR

T1 - Ischemic postconditioning: a clinical perspective

AU - Lønborg, Jacob

AU - Treiman, Marek

AU - Engstrøm, Thomas

PY - 2010/8

Y1 - 2010/8

N2 - Primary percutaneous coronary intervention is the recommended therapy for patients with STelevation myocardial infarction. However, restoration of coronary blood flow may lead to reperfusion injury, which has been suggested to account for 50% of the final myocardial infarct size. As an adjuvant therapy to primary percutaneous coronary intervention, ischemic postconditioning (IPost) has been shown to be safe and to underlie cardioprotection in several clinical trials. However, there remain important issues to be settled before IPost can be used routinely in patients undergoing primary percutaneous coronary intervention: first, determining which IPost protocol is the most optimal in humans; second, determining the effect of IPost on clinical outcome; third, determining in which patients should IPost be applied; and fourth, determining the effect on left ventricular function. This article discusses these issues with a clinical perspective and looks into alternative pharmacological cardioprotection.

AB - Primary percutaneous coronary intervention is the recommended therapy for patients with STelevation myocardial infarction. However, restoration of coronary blood flow may lead to reperfusion injury, which has been suggested to account for 50% of the final myocardial infarct size. As an adjuvant therapy to primary percutaneous coronary intervention, ischemic postconditioning (IPost) has been shown to be safe and to underlie cardioprotection in several clinical trials. However, there remain important issues to be settled before IPost can be used routinely in patients undergoing primary percutaneous coronary intervention: first, determining which IPost protocol is the most optimal in humans; second, determining the effect of IPost on clinical outcome; third, determining in which patients should IPost be applied; and fourth, determining the effect on left ventricular function. This article discusses these issues with a clinical perspective and looks into alternative pharmacological cardioprotection.

M3 - Review

VL - 2

SP - 579

EP - 589

JO - Interventional Cardiology

JF - Interventional Cardiology

SN - 0926-9649

IS - 4

ER -

ID: 33870466