In-vitro evaluation of the P-glycoprotein interactions of a series of potentially CNS-active Amaryllidaceae alkaloids
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Drug compounds interacting with the blood-brain barrier efflux transporter P-glycoprotein (P-gp) might have limited access to brain tissue. The aim of the present study was to evaluate whether nine potentially CNS-active Amaryllidaceae alkaloids of the crinine, lycorine and galanthamine types interact with P-gp.
Originalsprog | Engelsk |
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Tidsskrift | Journal of Pharmacy and Pharmacology |
Vol/bind | 64 |
Udgave nummer | 11 |
Sider (fra-til) | 1667-1677 |
Antal sider | 11 |
ISSN | 0022-3573 |
DOI | |
Status | Udgivet - 2012 |
ID: 44290044