International comparison of glycaemic control in people with type 1 diabetes: an update and extension
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International comparison of glycaemic control in people with type 1 diabetes : an update and extension. / Prigge, Regina; McKnight, John A.; Wild, Sarah H.; Haynes, Aveni; Jones, Timothy W.; Davis, Elizabeth A.; Rami-Merhar, Birgit; Fritsch, Maria; Prchla, Christine; Lavens, Astrid; Doggen, Kris; Chao, Suchsia; Aronson, Ronnie; Brown, Ruth; Ibfelt, Else H.; Svensson, Jannet; Young, Robert; Warner, Justin T.; Robinson, Holy; Laatikainen, Tiina; Rautiainen, Päivi; Delemer, Brigitte; Souchon, Pierre François; Diallo, Alpha M.; Holl, Reinhard W.; Schmid, Sebastian M.; Raile, Klemens; Tigas, Stelios; Bargiota, Alexandra; Zografou, Ioanna; Luk, Andrea O. Y.; Chan, Juliana C. N.; Dinneen, Sean F.; Buckley, Claire M.; Kgosidialwa, Oratile; Cherubini, Valentino; Gesuita, Rosaria; Strele, Ieva; Pildava, Santa; Veeze, Henk; Aanstoot, Henk-Jan; Mul, Dick; Jefferies, Craig; Cooper, John G.; Løvaas, Karianne Fjeld; Battelino, Tadej; Dovc, Klemen; Bratina, Nataša; Eeg-Olofsson, Katarina; Svensson, Ann-Marie; Gudbjornsdottir, Soffia; Globa, Evgenia; Zelinska, Nataliya.
I: Diabetic Medicine, Bind 39, Nr. 5, e14766, 2022.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - International comparison of glycaemic control in people with type 1 diabetes
T2 - an update and extension
AU - Prigge, Regina
AU - McKnight, John A.
AU - Wild, Sarah H.
AU - Haynes, Aveni
AU - Jones, Timothy W.
AU - Davis, Elizabeth A.
AU - Rami-Merhar, Birgit
AU - Fritsch, Maria
AU - Prchla, Christine
AU - Lavens, Astrid
AU - Doggen, Kris
AU - Chao, Suchsia
AU - Aronson, Ronnie
AU - Brown, Ruth
AU - Ibfelt, Else H.
AU - Svensson, Jannet
AU - Young, Robert
AU - Warner, Justin T.
AU - Robinson, Holy
AU - Laatikainen, Tiina
AU - Rautiainen, Päivi
AU - Delemer, Brigitte
AU - Souchon, Pierre François
AU - Diallo, Alpha M.
AU - Holl, Reinhard W.
AU - Schmid, Sebastian M.
AU - Raile, Klemens
AU - Tigas, Stelios
AU - Bargiota, Alexandra
AU - Zografou, Ioanna
AU - Luk, Andrea O. Y.
AU - Chan, Juliana C. N.
AU - Dinneen, Sean F.
AU - Buckley, Claire M.
AU - Kgosidialwa, Oratile
AU - Cherubini, Valentino
AU - Gesuita, Rosaria
AU - Strele, Ieva
AU - Pildava, Santa
AU - Veeze, Henk
AU - Aanstoot, Henk-Jan
AU - Mul, Dick
AU - Jefferies, Craig
AU - Cooper, John G.
AU - Løvaas, Karianne Fjeld
AU - Battelino, Tadej
AU - Dovc, Klemen
AU - Bratina, Nataša
AU - Eeg-Olofsson, Katarina
AU - Svensson, Ann-Marie
AU - Gudbjornsdottir, Soffia
AU - Globa, Evgenia
AU - Zelinska, Nataliya
N1 - © 2021 Diabetes UK.
PY - 2022
Y1 - 2022
N2 - AIMS: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes.METHODS: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c (IQR) and proportions of individuals with HbA1c < 58 mmol/mol (<7.5%), 58-74 mmol/mol (7.5-8.9%) and ≥75 mmol/mol (≥9.0%) were compared between populations for individuals aged <15, 15-24 and ≥25 years. Logistic regression was used to estimate the odds ratio (OR) of HbA1c < 58 mmol/mol (<7.5%) relative to ≥58 mmol/mol (≥7.5%), stratified and adjusted for sex, age and data source. Where possible, changes in the proportion of individuals in each HbA1c category compared to previous estimates were calculated.RESULTS: Median HbA1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA1c < 58 mmol/mol (<7.5%) were 0.91 (0.90-0.92) for women compared to men, 1.68 (1.65-1.71) for people aged <15 years and 0.81 (0.79-0.82) aged15-24 years compared to those aged ≥25 years. Differences between populations persisted after adjusting for sex, age and data source. In general, compared to our previous analysis, the proportion of people with an HbA1c < 58 mmol/l (<7.5%) increased and proportions of people with HbA1c ≥ 75 mmol/mol (≥9.0%) decreased.CONCLUSIONS: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes.
AB - AIMS: To update and extend a previous cross-sectional international comparison of glycaemic control in people with type 1 diabetes.METHODS: Data were obtained for 520,392 children and adults with type 1 diabetes from 17 population and five clinic-based data sources in countries or regions between 2016 and 2020. Median HbA1c (IQR) and proportions of individuals with HbA1c < 58 mmol/mol (<7.5%), 58-74 mmol/mol (7.5-8.9%) and ≥75 mmol/mol (≥9.0%) were compared between populations for individuals aged <15, 15-24 and ≥25 years. Logistic regression was used to estimate the odds ratio (OR) of HbA1c < 58 mmol/mol (<7.5%) relative to ≥58 mmol/mol (≥7.5%), stratified and adjusted for sex, age and data source. Where possible, changes in the proportion of individuals in each HbA1c category compared to previous estimates were calculated.RESULTS: Median HbA1c varied from 55 to 79 mmol/mol (7.2 to 9.4%) across data sources and age groups so a pooled estimate was deemed inappropriate. OR (95% CI) for HbA1c < 58 mmol/mol (<7.5%) were 0.91 (0.90-0.92) for women compared to men, 1.68 (1.65-1.71) for people aged <15 years and 0.81 (0.79-0.82) aged15-24 years compared to those aged ≥25 years. Differences between populations persisted after adjusting for sex, age and data source. In general, compared to our previous analysis, the proportion of people with an HbA1c < 58 mmol/l (<7.5%) increased and proportions of people with HbA1c ≥ 75 mmol/mol (≥9.0%) decreased.CONCLUSIONS: Glycaemic control of type 1 diabetes continues to vary substantially between age groups and data sources. While some improvement over time has been observed, glycaemic control remains sub-optimal for most people with Type 1 diabetes.
U2 - 10.1111/dme.14766
DO - 10.1111/dme.14766
M3 - Journal article
C2 - 34890078
VL - 39
JO - Diabetic Medicine
JF - Diabetic Medicine
SN - 0742-3071
IS - 5
M1 - e14766
ER -
ID: 301081691