Immunterapi til patienter med malignt melanom og hjernemetastaser
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Immunterapi til patienter med malignt melanom og hjernemetastaser. / Simonsen, Line Thing; Schmidt, Anne Mette Sjørslev; Øllegaard, Trine Heide; Svane, Inge Marie; Bastholt, Lars; Luczak, Adam Andrzej; Schmidt, Henrik.
I: Ugeskrift for Laeger, Bind 181, Nr. 24, V01190057, 2019.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Immunterapi til patienter med malignt melanom og hjernemetastaser
AU - Simonsen, Line Thing
AU - Schmidt, Anne Mette Sjørslev
AU - Øllegaard, Trine Heide
AU - Svane, Inge Marie
AU - Bastholt, Lars
AU - Luczak, Adam Andrzej
AU - Schmidt, Henrik
PY - 2019
Y1 - 2019
N2 - Melanoma has a high propensity to form brain metastases, and in this review, we discuss the treatment options for brain metastases. These have previously been sparse, but with the introduction of targeted therapy and checkpoint inhibitors, studies including patients with brain metastases have been published. Recent studies investigating combination of either dabrafenib and trametinib or ipilimumab and nivolumab have proved promising. Based on phase II studies, the most effective treatment for patients with asymptomatic brain metastases seems to be ipilimumab and nivolumab. Symptomatic brain metastases are presently being further investigated.
AB - Melanoma has a high propensity to form brain metastases, and in this review, we discuss the treatment options for brain metastases. These have previously been sparse, but with the introduction of targeted therapy and checkpoint inhibitors, studies including patients with brain metastases have been published. Recent studies investigating combination of either dabrafenib and trametinib or ipilimumab and nivolumab have proved promising. Based on phase II studies, the most effective treatment for patients with asymptomatic brain metastases seems to be ipilimumab and nivolumab. Symptomatic brain metastases are presently being further investigated.
M3 - Tidsskriftartikel
C2 - 31267950
VL - 181
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 24
M1 - V01190057
ER -
ID: 238526523