Imaging techniques used for the real-time assessment of angiogenesis in digestive cancers
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Imaging techniques used for the real-time assessment of angiogenesis in digestive cancers. / Saftoiu, Adrian; Vilmann, Peter; Săftoiu, Adrian.
I: World Journal of Gastroenterology, Bind 17, Nr. 1, 2011, s. 7-8.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Imaging techniques used for the real-time assessment of angiogenesis in digestive cancers
AU - Saftoiu, Adrian
AU - Vilmann, Peter
AU - Săftoiu, Adrian
PY - 2011
Y1 - 2011
N2 - Angiogenesis has a critical role in primary tumor growth and the development of metastases. Several angiogenesis inhibitors were recently developed, being a very attractive target for digestive tumor therapy. However, individualized therapy should not only be based on the pre-treatment imaging evaluation, but also on sensitive monitoring of microvascular changes during treatment. State-of-the-art imaging techniques have the potential to visualize and characterize angiogenesis, although the technology and methodologies employed are recent and need further validation. The aim of this series of reviews was to analyze and enhance current knowledge and future perspectives about the real-time assessment of angiogenesis in digestive cancers, used for the longitudinal monitoring of the effects of chemo-radiotherapy (including anti-angiogenic therapies), as well as for the precise targeting of drugs through molecular-based drug-delivery systems.
AB - Angiogenesis has a critical role in primary tumor growth and the development of metastases. Several angiogenesis inhibitors were recently developed, being a very attractive target for digestive tumor therapy. However, individualized therapy should not only be based on the pre-treatment imaging evaluation, but also on sensitive monitoring of microvascular changes during treatment. State-of-the-art imaging techniques have the potential to visualize and characterize angiogenesis, although the technology and methodologies employed are recent and need further validation. The aim of this series of reviews was to analyze and enhance current knowledge and future perspectives about the real-time assessment of angiogenesis in digestive cancers, used for the longitudinal monitoring of the effects of chemo-radiotherapy (including anti-angiogenic therapies), as well as for the precise targeting of drugs through molecular-based drug-delivery systems.
U2 - http://dx.doi.org/10.3748/wjg.v17.i1.7
DO - http://dx.doi.org/10.3748/wjg.v17.i1.7
M3 - Journal article
VL - 17
SP - 7
EP - 8
JO - World Chinese Journal of Digestology
JF - World Chinese Journal of Digestology
SN - 1009-3079
IS - 1
ER -
ID: 40202887