Human health hazard from antimicrobial-resistant enterococci in animals and food
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Standard
Human health hazard from antimicrobial-resistant enterococci in animals and food. / Heuer, Ole E; Hammerum, Anette M; Collignon, Peter; Wegener, Henrik Caspar.
I: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Bind 43, Nr. 7, 01.10.2006, s. 911-6.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Human health hazard from antimicrobial-resistant enterococci in animals and food
AU - Heuer, Ole E
AU - Hammerum, Anette M
AU - Collignon, Peter
AU - Wegener, Henrik Caspar
PY - 2006/10/1
Y1 - 2006/10/1
N2 - The use of antimicrobial agents in the modern farm industry has created a reservoir of resistant bacteria in food animals. Foods of animal origin are often contaminated with enterococci that are likely to contribute resistance genes, virulence factors, or other properties to enterococci IN humans. The potential hazard to human health from antimicrobial-resistant enterococci in animals is questioned by some scientists because of evidence of host specificity of enterococci. Similarly, the occurrences of specific nosocomial clones of enterococci in hospitals have lead to the misconception that antimicrobial-resistant animal enterococci should be disregarded as a human health hazard. On the basis of review of the literature, we find that neither the results provided by molecular typing that classify enterococci as host-specific organisms nor the occurrence of specific nosocomial clones of enterococci provide reasons to change the current view that antimicrobial-resistant enterococci from animals pose a threat to human health. On the contrary, antimicrobial resistance genes appear to spread freely between enterococci from different reservoirs, irrespective of their apparent host association.
AB - The use of antimicrobial agents in the modern farm industry has created a reservoir of resistant bacteria in food animals. Foods of animal origin are often contaminated with enterococci that are likely to contribute resistance genes, virulence factors, or other properties to enterococci IN humans. The potential hazard to human health from antimicrobial-resistant enterococci in animals is questioned by some scientists because of evidence of host specificity of enterococci. Similarly, the occurrences of specific nosocomial clones of enterococci in hospitals have lead to the misconception that antimicrobial-resistant animal enterococci should be disregarded as a human health hazard. On the basis of review of the literature, we find that neither the results provided by molecular typing that classify enterococci as host-specific organisms nor the occurrence of specific nosocomial clones of enterococci provide reasons to change the current view that antimicrobial-resistant enterococci from animals pose a threat to human health. On the contrary, antimicrobial resistance genes appear to spread freely between enterococci from different reservoirs, irrespective of their apparent host association.
KW - Adaptation, Physiological
KW - Animal Feed
KW - Animals
KW - Animals, Domestic
KW - Anti-Infective Agents
KW - Drug Resistance, Bacterial
KW - Enterococcus
KW - Gene Transfer Techniques
KW - Hazardous Substances
KW - Hospitals
KW - Humans
KW - Journal Article
U2 - 10.1086/507534
DO - 10.1086/507534
M3 - Journal article
C2 - 16941376
VL - 43
SP - 911
EP - 916
JO - Clinical Infectious Diseases
JF - Clinical Infectious Diseases
SN - 1058-4838
IS - 7
ER -
ID: 172813505