Hemiplegic migraine aura begins with cerebral hypoperfusion: imaging in the acute phase
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Hemiplegic migraine aura begins with cerebral hypoperfusion : imaging in the acute phase. / Hansen, Jakob M; Schytz, Henrik W; Larsen, Vibeke A; Iversen, Helle K; Ashina, Messoud.
I: Headache, Bind 51, Nr. 8, 2011, s. 1289-96.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Hemiplegic migraine aura begins with cerebral hypoperfusion
T2 - imaging in the acute phase
AU - Hansen, Jakob M
AU - Schytz, Henrik W
AU - Larsen, Vibeke A
AU - Iversen, Helle K
AU - Ashina, Messoud
N1 - © 2011 American Headache Society.
PY - 2011
Y1 - 2011
N2 - Imaging studies of spontaneous migraine aura have proved challenging because of the episodic and unpredictable nature of migraine attacks. Two patients with signs of acute ischemic stroke were evaluated for thrombolysis and turned out to suffer from familial hemiplegic migraine. It was possible to record the early phase of the hemiplegic aura with computed tomography with perfusion sequences and magnetic resonance imaging. We found cerebral hypoperfusion in the relevant cortical areas within the first hour after onset of aura symptoms. This report supports the concept that migraine aura across the migraine spectrum is caused by similar mechanisms. In a setting with efficient cooperation between headache and stroke neurologists, thrombolysis centers provide the set-up and opportunity to record aura symptoms at an early phase. Furthermore, in the time of ready access to acute systemic thrombolysis treatment, these cases underscore the importance of an accurate headache history, especially in younger patients.
AB - Imaging studies of spontaneous migraine aura have proved challenging because of the episodic and unpredictable nature of migraine attacks. Two patients with signs of acute ischemic stroke were evaluated for thrombolysis and turned out to suffer from familial hemiplegic migraine. It was possible to record the early phase of the hemiplegic aura with computed tomography with perfusion sequences and magnetic resonance imaging. We found cerebral hypoperfusion in the relevant cortical areas within the first hour after onset of aura symptoms. This report supports the concept that migraine aura across the migraine spectrum is caused by similar mechanisms. In a setting with efficient cooperation between headache and stroke neurologists, thrombolysis centers provide the set-up and opportunity to record aura symptoms at an early phase. Furthermore, in the time of ready access to acute systemic thrombolysis treatment, these cases underscore the importance of an accurate headache history, especially in younger patients.
U2 - http://dx.doi.org/10.1111/j.1526-4610.2011.01963.x
DO - http://dx.doi.org/10.1111/j.1526-4610.2011.01963.x
M3 - Journal article
VL - 51
SP - 1289
EP - 1296
JO - Headache
JF - Headache
SN - 0017-8748
IS - 8
ER -
ID: 40140789