Gender and autoimmune comorbidity in multiple sclerosis

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Standard

Gender and autoimmune comorbidity in multiple sclerosis. / Magyari, Melinda; Koch-Henriksen, Nils; Pfleger, Claudia C; Sørensen, Per Soelberg.

I: Multiple Sclerosis, Bind 20, Nr. 9, 05.02.2014, s. 1244-1251.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Magyari, M, Koch-Henriksen, N, Pfleger, CC & Sørensen, PS 2014, 'Gender and autoimmune comorbidity in multiple sclerosis', Multiple Sclerosis, bind 20, nr. 9, s. 1244-1251. https://doi.org/10.1177/1352458514521515

APA

Magyari, M., Koch-Henriksen, N., Pfleger, C. C., & Sørensen, P. S. (2014). Gender and autoimmune comorbidity in multiple sclerosis. Multiple Sclerosis, 20(9), 1244-1251. https://doi.org/10.1177/1352458514521515

Vancouver

Magyari M, Koch-Henriksen N, Pfleger CC, Sørensen PS. Gender and autoimmune comorbidity in multiple sclerosis. Multiple Sclerosis. 2014 feb. 5;20(9):1244-1251. https://doi.org/10.1177/1352458514521515

Author

Magyari, Melinda ; Koch-Henriksen, Nils ; Pfleger, Claudia C ; Sørensen, Per Soelberg. / Gender and autoimmune comorbidity in multiple sclerosis. I: Multiple Sclerosis. 2014 ; Bind 20, Nr. 9. s. 1244-1251.

Bibtex

@article{c8d2ed4c3dbc41f1b1abfaf8b16326cc,

title = "Gender and autoimmune comorbidity in multiple sclerosis",

abstract = "BACKGROUND: The female preponderance in incidence of multiple sclerosis (MS) calls for investigations into sex differences in comorbidity with other autoimmune diseases (ADs).OBJECTIVES: To determine whether male and female patients with MS have a higher frequency of autoimmune comorbidity than controls, and to describe the type and frequency of ADs that are associated with MS.METHODS: Our database was established by linkage of the Danish MS Registry to The Danish National Patient Register and consisted of 1403 patients of both sexes with clinical onset of MS between 2000 and 2004, and 25 matched controls for every case.RESULTS: None of the ADs occurred more frequently in female cases than in controls. Male cases were more likely to have Type I diabetes mellitus (odds ratio (OR) = 3.34; 95% CI 1.40 - 7.02; p < 0.008), Crohn's disease (OR = 5.03; 95% CI 1.18 - 16.10; p = 0.03) and systemic lupus erythematosus (OR = 12.55; 95% CI 1.62 - 69.95; p = 0.02) than male controls.CONCLUSIONS: Autoimmune disorders are rare, but some of them tend to occur together with MS at a higher rate than in controls. Although women are generally more prone to ADs than men, significantly increased occurrence of other ADs were only found in male MS patients.",

author = "Melinda Magyari and Nils Koch-Henriksen and Pfleger, {Claudia C} and S{\o}rensen, {Per Soelberg}",

note = "{\textcopyright} The Author(s) 2014.",

year = "2014",

month = feb,

day = "5",

doi = "10.1177/1352458514521515",

language = "English",

volume = "20",

pages = "1244--1251",

journal = "Multiple Sclerosis Journal",

issn = "1352-4585",

publisher = "SAGE Publications",

number = "9",

}

RIS

TY - JOUR

T1 - Gender and autoimmune comorbidity in multiple sclerosis

AU - Magyari, Melinda

AU - Koch-Henriksen, Nils

AU - Pfleger, Claudia C

AU - Sørensen, Per Soelberg

PY - 2014/2/5

Y1 - 2014/2/5

N2 - BACKGROUND: The female preponderance in incidence of multiple sclerosis (MS) calls for investigations into sex differences in comorbidity with other autoimmune diseases (ADs).OBJECTIVES: To determine whether male and female patients with MS have a higher frequency of autoimmune comorbidity than controls, and to describe the type and frequency of ADs that are associated with MS.METHODS: Our database was established by linkage of the Danish MS Registry to The Danish National Patient Register and consisted of 1403 patients of both sexes with clinical onset of MS between 2000 and 2004, and 25 matched controls for every case.RESULTS: None of the ADs occurred more frequently in female cases than in controls. Male cases were more likely to have Type I diabetes mellitus (odds ratio (OR) = 3.34; 95% CI 1.40 - 7.02; p < 0.008), Crohn's disease (OR = 5.03; 95% CI 1.18 - 16.10; p = 0.03) and systemic lupus erythematosus (OR = 12.55; 95% CI 1.62 - 69.95; p = 0.02) than male controls.CONCLUSIONS: Autoimmune disorders are rare, but some of them tend to occur together with MS at a higher rate than in controls. Although women are generally more prone to ADs than men, significantly increased occurrence of other ADs were only found in male MS patients.

AB - BACKGROUND: The female preponderance in incidence of multiple sclerosis (MS) calls for investigations into sex differences in comorbidity with other autoimmune diseases (ADs).OBJECTIVES: To determine whether male and female patients with MS have a higher frequency of autoimmune comorbidity than controls, and to describe the type and frequency of ADs that are associated with MS.METHODS: Our database was established by linkage of the Danish MS Registry to The Danish National Patient Register and consisted of 1403 patients of both sexes with clinical onset of MS between 2000 and 2004, and 25 matched controls for every case.RESULTS: None of the ADs occurred more frequently in female cases than in controls. Male cases were more likely to have Type I diabetes mellitus (odds ratio (OR) = 3.34; 95% CI 1.40 - 7.02; p < 0.008), Crohn's disease (OR = 5.03; 95% CI 1.18 - 16.10; p = 0.03) and systemic lupus erythematosus (OR = 12.55; 95% CI 1.62 - 69.95; p = 0.02) than male controls.CONCLUSIONS: Autoimmune disorders are rare, but some of them tend to occur together with MS at a higher rate than in controls. Although women are generally more prone to ADs than men, significantly increased occurrence of other ADs were only found in male MS patients.

U2 - 10.1177/1352458514521515

DO - 10.1177/1352458514521515

M3 - Journal article

C2 - 24500604

VL - 20

SP - 1244

EP - 1251

JO - Multiple Sclerosis Journal

JF - Multiple Sclerosis Journal

SN - 1352-4585

IS - 9

ER -

ID: 137672522