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Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia. / Thastrup, Maria; Marquart, Hanne Vibeke; Levinsen, Mette; Modvig, Signe; Abrahamsson, Jonas; Albertsen, Birgitte Klug; Frost, Britt Marie; Harila-Saari, Arja; Pesola, Jouni; Ulvmoen, Aina; Wojcik, Dorota Malgorzata; Taskinen, Mervi; Hoffmann, Marianne; Lausen, Birgitte; Schmiegelow, Kjeld; on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO).
I:
British Journal of Haematology, Bind 195, Nr. 1, 2021, s. 119-122.
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Harvard
Thastrup, M
, Marquart, HV, Levinsen, M, Modvig, S, Abrahamsson, J, Albertsen, BK, Frost, BM, Harila-Saari, A, Pesola, J, Ulvmoen, A, Wojcik, DM, Taskinen, M, Hoffmann, M, Lausen, B
, Schmiegelow, K & on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO) 2021, '
Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia',
British Journal of Haematology, bind 195, nr. 1, s. 119-122.
https://doi.org/10.1111/bjh.17769APA
Thastrup, M.
, Marquart, H. V., Levinsen, M., Modvig, S., Abrahamsson, J., Albertsen, B. K., Frost, B. M., Harila-Saari, A., Pesola, J., Ulvmoen, A., Wojcik, D. M., Taskinen, M., Hoffmann, M., Lausen, B.
, Schmiegelow, K., & on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO) (2021).
Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia.
British Journal of Haematology,
195(1), 119-122.
https://doi.org/10.1111/bjh.17769Vancouver
Thastrup M
, Marquart HV, Levinsen M, Modvig S, Abrahamsson J, Albertsen BK o.a.
Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia.
British Journal of Haematology. 2021;195(1):119-122.
https://doi.org/10.1111/bjh.17769Author
Thastrup, Maria ; Marquart, Hanne Vibeke ; Levinsen, Mette ; Modvig, Signe ; Abrahamsson, Jonas ; Albertsen, Birgitte Klug ; Frost, Britt Marie ; Harila-Saari, Arja ; Pesola, Jouni ; Ulvmoen, Aina ; Wojcik, Dorota Malgorzata ; Taskinen, Mervi ; Hoffmann, Marianne ; Lausen, Birgitte ; Schmiegelow, Kjeld ; on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO). / Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia. I: British Journal of Haematology. 2021 ; Bind 195, Nr. 1. s. 119-122.
Bibtex
@article{33827a6eeec64e7ca37b4eedbef5b0f5,
title = "Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia",
abstract = "Infants with acute lymphoblastic leukaemia (ALL) have a high frequency of central nervous system (CNS) involvement. Flow cytometric analysis of cerebrospinal fluid (CSF) was recently demonstrated to be a sensitive method for detecting CNS involvement in childhood ALL. In the present study, CSF from 14 infants was collected at routine lumbar punctures and analysed by multicolour flow cytometry. At initial diagnosis, leukaemic blasts were detected in CSF by flow cytometry in 11 patients (78·6%) compared to seven patients (50%) by cytospin. Larger studies are needed to determine if CSF flow cytometry has prognostic value in infant ALL.",
keywords = "ALL, central nervous system, cerebrospinal fluid, childhood, flow cytometry, metastasis",
author = "Maria Thastrup and Marquart, {Hanne Vibeke} and Mette Levinsen and Signe Modvig and Jonas Abrahamsson and Albertsen, {Birgitte Klug} and Frost, {Britt Marie} and Arja Harila-Saari and Jouni Pesola and Aina Ulvmoen and Wojcik, {Dorota Malgorzata} and Mervi Taskinen and Marianne Hoffmann and Birgitte Lausen and Kjeld Schmiegelow and {on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO)}",
note = "Publisher Copyright: {\textcopyright} 2021 British Society for Haematology and John Wiley & Sons Ltd",
year = "2021",
doi = "10.1111/bjh.17769",
language = "English",
volume = "195",
pages = "119--122",
journal = "British Journal of Haematology",
issn = "0007-1048",
publisher = "Wiley-Blackwell",
number = "1",
}
RIS
TY - JOUR
T1 - Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia
AU - Thastrup, Maria
AU - Marquart, Hanne Vibeke
AU - Levinsen, Mette
AU - Modvig, Signe
AU - Abrahamsson, Jonas
AU - Albertsen, Birgitte Klug
AU - Frost, Britt Marie
AU - Harila-Saari, Arja
AU - Pesola, Jouni
AU - Ulvmoen, Aina
AU - Wojcik, Dorota Malgorzata
AU - Taskinen, Mervi
AU - Hoffmann, Marianne
AU - Lausen, Birgitte
AU - Schmiegelow, Kjeld
AU - on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO)
N1 - Publisher Copyright:
© 2021 British Society for Haematology and John Wiley & Sons Ltd
PY - 2021
Y1 - 2021
N2 - Infants with acute lymphoblastic leukaemia (ALL) have a high frequency of central nervous system (CNS) involvement. Flow cytometric analysis of cerebrospinal fluid (CSF) was recently demonstrated to be a sensitive method for detecting CNS involvement in childhood ALL. In the present study, CSF from 14 infants was collected at routine lumbar punctures and analysed by multicolour flow cytometry. At initial diagnosis, leukaemic blasts were detected in CSF by flow cytometry in 11 patients (78·6%) compared to seven patients (50%) by cytospin. Larger studies are needed to determine if CSF flow cytometry has prognostic value in infant ALL.
AB - Infants with acute lymphoblastic leukaemia (ALL) have a high frequency of central nervous system (CNS) involvement. Flow cytometric analysis of cerebrospinal fluid (CSF) was recently demonstrated to be a sensitive method for detecting CNS involvement in childhood ALL. In the present study, CSF from 14 infants was collected at routine lumbar punctures and analysed by multicolour flow cytometry. At initial diagnosis, leukaemic blasts were detected in CSF by flow cytometry in 11 patients (78·6%) compared to seven patients (50%) by cytospin. Larger studies are needed to determine if CSF flow cytometry has prognostic value in infant ALL.
KW - ALL
KW - central nervous system
KW - cerebrospinal fluid
KW - childhood
KW - flow cytometry
KW - metastasis
U2 - 10.1111/bjh.17769
DO - 10.1111/bjh.17769
M3 - Journal article
C2 - 34396501
AN - SCOPUS:85112697821
VL - 195
SP - 119
EP - 122
JO - British Journal of Haematology
JF - British Journal of Haematology
SN - 0007-1048
IS - 1
ER -
