Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography

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Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography. / Fuchs, Andreas; Kühl, J Tobias; Chen, Marcus Y; Helqvist, Steffen; Razeto, Marco; Arakita, Kazumasa; Steveson, Chloe; Arai, Andrew E; Kofoed, Klaus F.

I: Journal of Cardiovascular Computed Tomography, Bind 9, Nr. 5, 21.06.2015, s. 393-8.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Fuchs, A, Kühl, JT, Chen, MY, Helqvist, S, Razeto, M, Arakita, K, Steveson, C, Arai, AE & Kofoed, KF 2015, 'Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography', Journal of Cardiovascular Computed Tomography, bind 9, nr. 5, s. 393-8. https://doi.org/10.1016/j.jcct.2015.03.016

APA

Fuchs, A., Kühl, J. T., Chen, M. Y., Helqvist, S., Razeto, M., Arakita, K., Steveson, C., Arai, A. E., & Kofoed, K. F. (2015). Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography. Journal of Cardiovascular Computed Tomography, 9(5), 393-8. https://doi.org/10.1016/j.jcct.2015.03.016

Vancouver

Fuchs A, Kühl JT, Chen MY, Helqvist S, Razeto M, Arakita K o.a. Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography. Journal of Cardiovascular Computed Tomography. 2015 jun. 21;9(5):393-8. https://doi.org/10.1016/j.jcct.2015.03.016

Author

Fuchs, Andreas ; Kühl, J Tobias ; Chen, Marcus Y ; Helqvist, Steffen ; Razeto, Marco ; Arakita, Kazumasa ; Steveson, Chloe ; Arai, Andrew E ; Kofoed, Klaus F. / Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography. I: Journal of Cardiovascular Computed Tomography. 2015 ; Bind 9, Nr. 5. s. 393-8.

Bibtex

@article{c7a9e3f3c5e5444c940859c71bdfdbe1,

title = "Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography",

abstract = "BACKGROUND: The reader confidence and diagnostic accuracy of coronary CT angiography (CCTA) can be compromised by the presence of calcified plaques and stents causing blooming artifacts. Compared to conventional invasive coronary angiography (ICA), this may cause an overestimation of stenosis severity leading to false-positive results. In a pilot study, we tested the feasibility of a new coronary calcium image subtraction algorithm in relation to reader confidence and diagnostic accuracy.METHODS: Forty-three patients underwent clinically indicated ICA and CCTA using a 320-detector row CT. Median Agatston score was 510. Two data sets were reconstructed: a conventional CCTA (CCTAconv) and a subtracted CCTA (CCTAsub), where calcifications detected on noncontrast images were subtracted from the CCTA. Reader confidence and concordance with ICA for identification of >50% stenosis were recorded. We defined target segments on CCTAconv as motion-free coronary segments with calcification or stent and low reader confidence. The effect of CCTAsub was assessed. No approval from the ethics committee was required according to Danish law.RESULTS: A total of 76 target segments were identified. The use of coronary calcium image subtraction improved the reader confidence in 66% of these segments. In target segments, specificity (86% vs 65%; P < .01) and positive predictive value (71% vs 51%, P = .03) were improved using CCTAsub compared to CCTAconv without loss in negative predictive value.CONCLUSIONS: Our initial experience with coronary calcium image subtraction suggests that it is feasible and could lead to an improvement in reader confidence and diagnostic accuracy for identification of significant coronary artery disease.",

author = "Andreas Fuchs and K{\"u}hl, {J Tobias} and Chen, {Marcus Y} and Steffen Helqvist and Marco Razeto and Kazumasa Arakita and Chloe Steveson and Arai, {Andrew E} and Kofoed, {Klaus F}",

year = "2015",

month = jun,

day = "21",

doi = "10.1016/j.jcct.2015.03.016",

language = "English",

volume = "9",

pages = "393--8",

journal = "Journal of Cardiovascular Computed Tomography",

issn = "1934-5925",

publisher = "Elsevier",

number = "5",

}

RIS

TY - JOUR

T1 - Feasibility of coronary calcium and stent image subtraction using 320-detector row CT angiography

AU - Fuchs, Andreas

AU - Kühl, J Tobias

AU - Chen, Marcus Y

AU - Helqvist, Steffen

AU - Razeto, Marco

AU - Arakita, Kazumasa

AU - Steveson, Chloe

AU - Arai, Andrew E

AU - Kofoed, Klaus F

PY - 2015/6/21

Y1 - 2015/6/21

N2 - BACKGROUND: The reader confidence and diagnostic accuracy of coronary CT angiography (CCTA) can be compromised by the presence of calcified plaques and stents causing blooming artifacts. Compared to conventional invasive coronary angiography (ICA), this may cause an overestimation of stenosis severity leading to false-positive results. In a pilot study, we tested the feasibility of a new coronary calcium image subtraction algorithm in relation to reader confidence and diagnostic accuracy.METHODS: Forty-three patients underwent clinically indicated ICA and CCTA using a 320-detector row CT. Median Agatston score was 510. Two data sets were reconstructed: a conventional CCTA (CCTAconv) and a subtracted CCTA (CCTAsub), where calcifications detected on noncontrast images were subtracted from the CCTA. Reader confidence and concordance with ICA for identification of >50% stenosis were recorded. We defined target segments on CCTAconv as motion-free coronary segments with calcification or stent and low reader confidence. The effect of CCTAsub was assessed. No approval from the ethics committee was required according to Danish law.RESULTS: A total of 76 target segments were identified. The use of coronary calcium image subtraction improved the reader confidence in 66% of these segments. In target segments, specificity (86% vs 65%; P < .01) and positive predictive value (71% vs 51%, P = .03) were improved using CCTAsub compared to CCTAconv without loss in negative predictive value.CONCLUSIONS: Our initial experience with coronary calcium image subtraction suggests that it is feasible and could lead to an improvement in reader confidence and diagnostic accuracy for identification of significant coronary artery disease.

AB - BACKGROUND: The reader confidence and diagnostic accuracy of coronary CT angiography (CCTA) can be compromised by the presence of calcified plaques and stents causing blooming artifacts. Compared to conventional invasive coronary angiography (ICA), this may cause an overestimation of stenosis severity leading to false-positive results. In a pilot study, we tested the feasibility of a new coronary calcium image subtraction algorithm in relation to reader confidence and diagnostic accuracy.METHODS: Forty-three patients underwent clinically indicated ICA and CCTA using a 320-detector row CT. Median Agatston score was 510. Two data sets were reconstructed: a conventional CCTA (CCTAconv) and a subtracted CCTA (CCTAsub), where calcifications detected on noncontrast images were subtracted from the CCTA. Reader confidence and concordance with ICA for identification of >50% stenosis were recorded. We defined target segments on CCTAconv as motion-free coronary segments with calcification or stent and low reader confidence. The effect of CCTAsub was assessed. No approval from the ethics committee was required according to Danish law.RESULTS: A total of 76 target segments were identified. The use of coronary calcium image subtraction improved the reader confidence in 66% of these segments. In target segments, specificity (86% vs 65%; P < .01) and positive predictive value (71% vs 51%, P = .03) were improved using CCTAsub compared to CCTAconv without loss in negative predictive value.CONCLUSIONS: Our initial experience with coronary calcium image subtraction suggests that it is feasible and could lead to an improvement in reader confidence and diagnostic accuracy for identification of significant coronary artery disease.

U2 - 10.1016/j.jcct.2015.03.016

DO - 10.1016/j.jcct.2015.03.016

M3 - Journal article

C2 - 26091841

VL - 9

SP - 393

EP - 398

JO - Journal of Cardiovascular Computed Tomography

JF - Journal of Cardiovascular Computed Tomography

SN - 1934-5925

IS - 5

ER -

ID: 162154603