Ethical considerations in crossing the xenobarrier
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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Ethical considerations in crossing the xenobarrier. / Mann, Sebastian Porsdam; Sun, Rosa; Hermerén, Göran.
Methods in Molecular Biology. Humana Press, 2019. s. 175-193 (Methods in Molecular Biology, Bind 2005).Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - Ethical considerations in crossing the xenobarrier
AU - Mann, Sebastian Porsdam
AU - Sun, Rosa
AU - Hermerén, Göran
PY - 2019
Y1 - 2019
N2 - Chimeras have been an important part of animal research for decades. Yet crossing the species barrier has always been seen as potentially morally problematic. In recent years, advances in chimeric research and the attendant possibilities—organ xenotransplantation, cognitive enhancement, and others—have given rise to further ethical concern. This contribution surveys the main ethical questions that have been discussed in the literature. We examine two arguments—from the order of nature and from human dignity—which aim to show that chimerization is inherently wrong. Finding the first untenable and the second largely inapplicable, we then turn to two unconvincing arguments designed to show that chimerization must necessarily lead to negative outcomes. Having thus found that no blanket statements can be made on the ethics of chimerization, we examine two important parameters relevant to the ethical evaluation of proposed chimeric research: The argument from moral status and from risk.
AB - Chimeras have been an important part of animal research for decades. Yet crossing the species barrier has always been seen as potentially morally problematic. In recent years, advances in chimeric research and the attendant possibilities—organ xenotransplantation, cognitive enhancement, and others—have given rise to further ethical concern. This contribution surveys the main ethical questions that have been discussed in the literature. We examine two arguments—from the order of nature and from human dignity—which aim to show that chimerization is inherently wrong. Finding the first untenable and the second largely inapplicable, we then turn to two unconvincing arguments designed to show that chimerization must necessarily lead to negative outcomes. Having thus found that no blanket statements can be made on the ethics of chimerization, we examine two important parameters relevant to the ethical evaluation of proposed chimeric research: The argument from moral status and from risk.
KW - Chimera
KW - Chimeric ethics
KW - Framework
KW - Moral
KW - Xenobarrier
UR - https://www.mendeley.com/catalogue/c250f94e-a0dd-37b2-abf4-44e15ba8f260/
U2 - 10.1007/978-1-4939-9524-0_12
DO - 10.1007/978-1-4939-9524-0_12
M3 - Bidrag til bog/antologi
C2 - 31175653
T3 - Methods in Molecular Biology
SP - 175
EP - 193
BT - Methods in Molecular Biology
PB - Humana Press
ER -
ID: 383103927