Emotional and Behavioral Trajectories of 2 to 9 Years Old Children Born to Opioid-Dependent Mothers
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Emotional and Behavioral Trajectories of 2 to 9 Years Old Children Born to Opioid-Dependent Mothers. / Jaekel, Julia; Kim, Hyun M.; Lee, Samantha J.; Schwartz, Ashlyn; Henderson, Jacqueline M.T.; Woodward, Lianne J.
I: Research on Child and Adolescent Psychopathology, Bind 49, Nr. 4, 04.2021, s. 443-457.Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
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TY - JOUR
T1 - Emotional and Behavioral Trajectories of 2 to 9 Years Old Children Born to Opioid-Dependent Mothers
AU - Jaekel, Julia
AU - Kim, Hyun M.
AU - Lee, Samantha J.
AU - Schwartz, Ashlyn
AU - Henderson, Jacqueline M.T.
AU - Woodward, Lianne J.
N1 - Publisher Copyright: © 2021, The Author(s).
PY - 2021/4
Y1 - 2021/4
N2 - Maternal opioid use in pregnancy has increased dramatically. Knowledge about children’s longer-term emotional and behavioral development after prenatal opioid exposure is scarce. A regional sample of 89 opioid-exposed and 104 non-exposed comparison children were studied prospectively at ages 2, 4.5, and 9 years using the Strengths and Difficulties Questionnaire (SDQ) completed by primary caregivers. Across all childhood assessments, opioid-exposed children obtained significantly higher total difficulties scores than non-exposed comparison children. Growth curve modeling revealed that, relative to their same age peers, opioid-exposed children’s emotional and behavioral difficulties significantly worsened over time. Moreover, fixed effects estimates showed that total difficulties trajectories were poorer for children subject to higher prenatal risk (Est = 1.78, 95% CI = [0.46, 3.09]) who were born to mothers with high levels of social adversity (1.11 [0.51, 1.71]), and were then raised in families characterized by high levels of psychosocial risk (1.94 [0.90, 2.98]) and unstable caregiving (1.91 [0.33, 3.48]). A complex set of pre- and postnatal processes contribute to opioid-exposed children’s emotional and behavioral development. Efforts to mitigate the long-term consequences of opioid use in pregnancy need to consider both children’s and their caregivers’ biopsychosocial risks.
AB - Maternal opioid use in pregnancy has increased dramatically. Knowledge about children’s longer-term emotional and behavioral development after prenatal opioid exposure is scarce. A regional sample of 89 opioid-exposed and 104 non-exposed comparison children were studied prospectively at ages 2, 4.5, and 9 years using the Strengths and Difficulties Questionnaire (SDQ) completed by primary caregivers. Across all childhood assessments, opioid-exposed children obtained significantly higher total difficulties scores than non-exposed comparison children. Growth curve modeling revealed that, relative to their same age peers, opioid-exposed children’s emotional and behavioral difficulties significantly worsened over time. Moreover, fixed effects estimates showed that total difficulties trajectories were poorer for children subject to higher prenatal risk (Est = 1.78, 95% CI = [0.46, 3.09]) who were born to mothers with high levels of social adversity (1.11 [0.51, 1.71]), and were then raised in families characterized by high levels of psychosocial risk (1.94 [0.90, 2.98]) and unstable caregiving (1.91 [0.33, 3.48]). A complex set of pre- and postnatal processes contribute to opioid-exposed children’s emotional and behavioral development. Efforts to mitigate the long-term consequences of opioid use in pregnancy need to consider both children’s and their caregivers’ biopsychosocial risks.
KW - Biopsychosocial risk
KW - Developmental trajectories
KW - Neonatal abstinence/opioid withdrawal syndrome (NAS/NOWS)
KW - Opioids
UR - http://www.scopus.com/inward/record.url?scp=85099383088&partnerID=8YFLogxK
U2 - 10.1007/s10802-020-00766-w
DO - 10.1007/s10802-020-00766-w
M3 - Journal article
C2 - 33433780
AN - SCOPUS:85099383088
VL - 49
SP - 443
EP - 457
JO - Research on Child and Adolescent Psychopathology
JF - Research on Child and Adolescent Psychopathology
SN - 2730-7166
IS - 4
ER -
ID: 393156789