Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Standard

Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges. / Kegnæs, Marina; Novovic, Srdan; Shabanzadeh, Daniel Mønsted.

I: Journal of Clinical Medicine, Bind 12, Nr. 14, 4802, 2023.

Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt

Harvard

Kegnæs, M, Novovic, S & Shabanzadeh, DM 2023, 'Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges', Journal of Clinical Medicine, bind 12, nr. 14, 4802. https://doi.org/10.3390/jcm12144802

APA

Kegnæs, M., Novovic, S., & Shabanzadeh, D. M. (2023). Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges. Journal of Clinical Medicine, 12(14), [4802]. https://doi.org/10.3390/jcm12144802

Vancouver

Kegnæs M, Novovic S, Shabanzadeh DM. Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges. Journal of Clinical Medicine. 2023;12(14). 4802. https://doi.org/10.3390/jcm12144802

Author

Kegnæs, Marina ; Novovic, Srdan ; Shabanzadeh, Daniel Mønsted. / Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges. I: Journal of Clinical Medicine. 2023 ; Bind 12, Nr. 14.

Bibtex

@article{896b9cef5497428287ec62f188832cb4,

title = "Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges",

abstract = "Biliary Sphincter of Oddi dysfunction (SOD) is one of the main causes of post-cholecystectomy pain. In this review, we aimed to provide an update on the current knowledge on biliary SOD, with an emphasis on diagnostics and therapy. Overall, current but scarce data support biliary sphincterotomy for patients with type 1 and 2 SOD, but not for type 3. However, sphincterotomy is associated with post-treatment pancreatitis rates of from 10% to 15%, thus calling for improved diagnostics, patient selection and treatment modalities for SOD. The role of pharmacologic therapy for patients with SOD is poorly explored and only two randomized controlled trials are available. Currently, studies comparing treatment outcomes are few. There is an unmet need for randomized sham/placebo-controlled clinical trials related to both pharmacological and non-pharmacological treatments of SOD.",

keywords = "cholecystectomy, cholescintigraphy, post-cholecystectomy pain, sphincter of Oddi dysfunction (SOD), sphincterotomy",

author = "Marina Kegn{\ae}s and Srdan Novovic and Shabanzadeh, {Daniel M{\o}nsted}",

note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

doi = "10.3390/jcm12144802",

language = "English",

volume = "12",

journal = "Journal of Clinical Medicine",

issn = "2077-0383",

publisher = "M D P I AG",

number = "14",

}

RIS

TY - JOUR

T1 - Dysfunction of Biliary Sphincter of Oddi—Clinical, Diagnostic and Treatment Challenges

AU - Kegnæs, Marina

AU - Novovic, Srdan

AU - Shabanzadeh, Daniel Mønsted

PY - 2023

Y1 - 2023

N2 - Biliary Sphincter of Oddi dysfunction (SOD) is one of the main causes of post-cholecystectomy pain. In this review, we aimed to provide an update on the current knowledge on biliary SOD, with an emphasis on diagnostics and therapy. Overall, current but scarce data support biliary sphincterotomy for patients with type 1 and 2 SOD, but not for type 3. However, sphincterotomy is associated with post-treatment pancreatitis rates of from 10% to 15%, thus calling for improved diagnostics, patient selection and treatment modalities for SOD. The role of pharmacologic therapy for patients with SOD is poorly explored and only two randomized controlled trials are available. Currently, studies comparing treatment outcomes are few. There is an unmet need for randomized sham/placebo-controlled clinical trials related to both pharmacological and non-pharmacological treatments of SOD.

AB - Biliary Sphincter of Oddi dysfunction (SOD) is one of the main causes of post-cholecystectomy pain. In this review, we aimed to provide an update on the current knowledge on biliary SOD, with an emphasis on diagnostics and therapy. Overall, current but scarce data support biliary sphincterotomy for patients with type 1 and 2 SOD, but not for type 3. However, sphincterotomy is associated with post-treatment pancreatitis rates of from 10% to 15%, thus calling for improved diagnostics, patient selection and treatment modalities for SOD. The role of pharmacologic therapy for patients with SOD is poorly explored and only two randomized controlled trials are available. Currently, studies comparing treatment outcomes are few. There is an unmet need for randomized sham/placebo-controlled clinical trials related to both pharmacological and non-pharmacological treatments of SOD.

KW - cholecystectomy

KW - cholescintigraphy

KW - post-cholecystectomy pain

KW - sphincter of Oddi dysfunction (SOD)

KW - sphincterotomy

U2 - 10.3390/jcm12144802

DO - 10.3390/jcm12144802

M3 - Review

C2 - 37510917

AN - SCOPUS:85166284372

VL - 12

JO - Journal of Clinical Medicine

JF - Journal of Clinical Medicine

SN - 2077-0383

IS - 14

M1 - 4802

ER -

ID: 369130220