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Differences in radiotherapy delivery and outcome due to contouring variation. / Hollensen, Christian; Persson, Gitte; Højgaard, Liselotte; Specht, Lena; Larsen, Rasmus.
Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers. Springer Verlag, 2013. s. 122-129 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Bind 7761 LNCS).
Publikation: Bidrag til bog/antologi/rapport › Konferencebidrag i proceedings › Forskning › fagfællebedømt
Harvard
Hollensen, C
, Persson, G, Højgaard, L, Specht, L & Larsen, R 2013,
Differences in radiotherapy delivery and outcome due to contouring variation. i
Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers. Springer Verlag, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), bind 7761 LNCS, s. 122-129, International Workshop on Clinical Image-Based Procedures: From Planning to Intervention, CLIP 2012 - Held in Conjunction with MICCAI 2012, Nice, Frankrig,
05/10/2012.
https://doi.org/10.1007/978-3-642-38079-2_16APA
Hollensen, C.
, Persson, G., Højgaard, L., Specht, L., & Larsen, R. (2013).
Differences in radiotherapy delivery and outcome due to contouring variation. I
Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers (s. 122-129). Springer Verlag. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) Bind 7761 LNCS
https://doi.org/10.1007/978-3-642-38079-2_16Vancouver
Hollensen C
, Persson G, Højgaard L, Specht L, Larsen R.
Differences in radiotherapy delivery and outcome due to contouring variation. I Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers. Springer Verlag. 2013. s. 122-129. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Bind 7761 LNCS).
https://doi.org/10.1007/978-3-642-38079-2_16Author
Hollensen, Christian ; Persson, Gitte ; Højgaard, Liselotte ; Specht, Lena ; Larsen, Rasmus. / Differences in radiotherapy delivery and outcome due to contouring variation. Clinical Image-Based Procedures: From Planning to Intervention - International Workshop, CLIP 2012, Held in Conjunction with MICCAI 2012, Revised Selected Papers. Springer Verlag, 2013. s. 122-129 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), Bind 7761 LNCS).
Bibtex
@inproceedings{4c5c6d38a8a34fa681de71c2b9677bf0,
title = "Differences in radiotherapy delivery and outcome due to contouring variation",
abstract = "Gross tumor volume (GTV) delineation is central for radiotherapy planning. It provides the basis of the clinical target volume and, ultimately, the planning target volume which is used for dose optimization. Manual GTV delineations are prone to intra- and inter-observer variation and automatic segmentation methods also produce different results. There is no consensus on how to account for the contouring uncertainty, but has been suggested to incorporate it into the planning target volume (PTV) margin. Current recipes for the PTV margin are based on normal distribution assumptions and are more suitable for setup and execution errors. In this study we use the GTV delineations made by 6 experienced clinicians to create delineation-specific dose plans. These dose plans are then used to calculate theoretic tumor control probabilities (TCP) differences between delineations. The results show that current margin recipes are inadequate for maintaining the same TCP despite manual delineation variation. New methods to account for delineation variation should be developed.",
keywords = "Contouring observer variation, Dose planning, Lung tumor, Radiotherapy, Tumor control probability",
author = "Christian Hollensen and Gitte Persson and Liselotte H{\o}jgaard and Lena Specht and Rasmus Larsen",
year = "2013",
doi = "10.1007/978-3-642-38079-2_16",
language = "English",
isbn = "9783642380785",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "122--129",
booktitle = "Clinical Image-Based Procedures",
address = "Germany",
note = "International Workshop on Clinical Image-Based Procedures: From Planning to Intervention, CLIP 2012 - Held in Conjunction with MICCAI 2012 ; Conference date: 05-10-2012 Through 05-10-2012",
}
RIS
TY - GEN
T1 - Differences in radiotherapy delivery and outcome due to contouring variation
AU - Hollensen, Christian
AU - Persson, Gitte
AU - Højgaard, Liselotte
AU - Specht, Lena
AU - Larsen, Rasmus
PY - 2013
Y1 - 2013
N2 - Gross tumor volume (GTV) delineation is central for radiotherapy planning. It provides the basis of the clinical target volume and, ultimately, the planning target volume which is used for dose optimization. Manual GTV delineations are prone to intra- and inter-observer variation and automatic segmentation methods also produce different results. There is no consensus on how to account for the contouring uncertainty, but has been suggested to incorporate it into the planning target volume (PTV) margin. Current recipes for the PTV margin are based on normal distribution assumptions and are more suitable for setup and execution errors. In this study we use the GTV delineations made by 6 experienced clinicians to create delineation-specific dose plans. These dose plans are then used to calculate theoretic tumor control probabilities (TCP) differences between delineations. The results show that current margin recipes are inadequate for maintaining the same TCP despite manual delineation variation. New methods to account for delineation variation should be developed.
AB - Gross tumor volume (GTV) delineation is central for radiotherapy planning. It provides the basis of the clinical target volume and, ultimately, the planning target volume which is used for dose optimization. Manual GTV delineations are prone to intra- and inter-observer variation and automatic segmentation methods also produce different results. There is no consensus on how to account for the contouring uncertainty, but has been suggested to incorporate it into the planning target volume (PTV) margin. Current recipes for the PTV margin are based on normal distribution assumptions and are more suitable for setup and execution errors. In this study we use the GTV delineations made by 6 experienced clinicians to create delineation-specific dose plans. These dose plans are then used to calculate theoretic tumor control probabilities (TCP) differences between delineations. The results show that current margin recipes are inadequate for maintaining the same TCP despite manual delineation variation. New methods to account for delineation variation should be developed.
KW - Contouring observer variation
KW - Dose planning
KW - Lung tumor
KW - Radiotherapy
KW - Tumor control probability
UR - http://www.scopus.com/inward/record.url?scp=84893064481&partnerID=8YFLogxK
U2 - 10.1007/978-3-642-38079-2_16
DO - 10.1007/978-3-642-38079-2_16
M3 - Article in proceedings
AN - SCOPUS:84893064481
SN - 9783642380785
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 122
EP - 129
BT - Clinical Image-Based Procedures
PB - Springer Verlag
T2 - International Workshop on Clinical Image-Based Procedures: From Planning to Intervention, CLIP 2012 - Held in Conjunction with MICCAI 2012
Y2 - 5 October 2012 through 5 October 2012
ER -
