Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise

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Standard

Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome : an OMERACT reliability exercise. / Hočevar, Alojzija; Bruyn, George A.; Terslev, Lene; De Agustin, Juan Jose; MacCarter, Daryl; Chrysidis, Stavros; Collado, Paz; Dejaco, Christian; Fana, Viktoria; Filippou, Georgios; Finzel, Stephanie; Gandjbakhch, Frederique; Hanova, Petra; Hammenfors, Daniel; Hernandez-Diaz, Cristina; Iagnocco, Annamaria; Mortada, Mohamed Atia; Inanc, Nevsun; Naredo, Esperanza; Ohrndorf, Sarah; Perko, Nejc; Schmidt, Wolfgang A.; Tamborrini, Giorgio; Tomšič, Matija; Chary-Valckenaere, Isabelle; Zabotti, Alen; Keen, Helen I.; Pineda, Carlos; D'Agostino, Maria Antonietta; Jousse-Joulin, Sandrine.

I: Rheumatology, Bind 61, Nr. 8, 2022, s. 3341-3350.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Hočevar, A, Bruyn, GA, Terslev, L, De Agustin, JJ, MacCarter, D, Chrysidis, S, Collado, P, Dejaco, C, Fana, V, Filippou, G, Finzel, S, Gandjbakhch, F, Hanova, P, Hammenfors, D, Hernandez-Diaz, C, Iagnocco, A, Mortada, MA, Inanc, N, Naredo, E, Ohrndorf, S, Perko, N, Schmidt, WA, Tamborrini, G, Tomšič, M, Chary-Valckenaere, I, Zabotti, A, Keen, HI, Pineda, C, D'Agostino, MA & Jousse-Joulin, S 2022, 'Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise', Rheumatology, bind 61, nr. 8, s. 3341-3350. https://doi.org/10.1093/rheumatology/keab876

APA

Hočevar, A., Bruyn, G. A., Terslev, L., De Agustin, J. J., MacCarter, D., Chrysidis, S., Collado, P., Dejaco, C., Fana, V., Filippou, G., Finzel, S., Gandjbakhch, F., Hanova, P., Hammenfors, D., Hernandez-Diaz, C., Iagnocco, A., Mortada, M. A., Inanc, N., Naredo, E., ... Jousse-Joulin, S. (2022). Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise. Rheumatology, 61(8), 3341-3350. https://doi.org/10.1093/rheumatology/keab876

Vancouver

Hočevar A, Bruyn GA, Terslev L, De Agustin JJ, MacCarter D, Chrysidis S o.a. Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome: an OMERACT reliability exercise. Rheumatology. 2022;61(8):3341-3350. https://doi.org/10.1093/rheumatology/keab876

Author

Hočevar, Alojzija ; Bruyn, George A. ; Terslev, Lene ; De Agustin, Juan Jose ; MacCarter, Daryl ; Chrysidis, Stavros ; Collado, Paz ; Dejaco, Christian ; Fana, Viktoria ; Filippou, Georgios ; Finzel, Stephanie ; Gandjbakhch, Frederique ; Hanova, Petra ; Hammenfors, Daniel ; Hernandez-Diaz, Cristina ; Iagnocco, Annamaria ; Mortada, Mohamed Atia ; Inanc, Nevsun ; Naredo, Esperanza ; Ohrndorf, Sarah ; Perko, Nejc ; Schmidt, Wolfgang A. ; Tamborrini, Giorgio ; Tomšič, Matija ; Chary-Valckenaere, Isabelle ; Zabotti, Alen ; Keen, Helen I. ; Pineda, Carlos ; D'Agostino, Maria Antonietta ; Jousse-Joulin, Sandrine. / Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome : an OMERACT reliability exercise. I: Rheumatology. 2022 ; Bind 61, Nr. 8. s. 3341-3350.

Bibtex

@article{440171e1863e4c38a092a0137923a9ac,
title = "Development of a new ultrasound scoring system to evaluate glandular inflammation in Sj{\"o}gren's syndrome: an OMERACT reliability exercise",
abstract = "OBJECTIVE: The aim of this exercise from the OMERACT Ultrasound subgroup on Sj{\"o}gren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sj{\"o}gren's syndrome (pSS). METHODS: Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. RESULTS: The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. CONCLUSION: The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.",
keywords = "colour Doppler ultrasound, primary Sj{\"o}gren{\textquoteright}s syndrome, salivary gland vascularization, scoring system",
author = "Alojzija Ho{\v c}evar and Bruyn, {George A.} and Lene Terslev and {De Agustin}, {Juan Jose} and Daryl MacCarter and Stavros Chrysidis and Paz Collado and Christian Dejaco and Viktoria Fana and Georgios Filippou and Stephanie Finzel and Frederique Gandjbakhch and Petra Hanova and Daniel Hammenfors and Cristina Hernandez-Diaz and Annamaria Iagnocco and Mortada, {Mohamed Atia} and Nevsun Inanc and Esperanza Naredo and Sarah Ohrndorf and Nejc Perko and Schmidt, {Wolfgang A.} and Giorgio Tamborrini and Matija Tom{\v s}i{\v c} and Isabelle Chary-Valckenaere and Alen Zabotti and Keen, {Helen I.} and Carlos Pineda and D'Agostino, {Maria Antonietta} and Sandrine Jousse-Joulin",
note = "Publisher Copyright: {\textcopyright} The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.",
year = "2022",
doi = "10.1093/rheumatology/keab876",
language = "English",
volume = "61",
pages = "3341--3350",
journal = "Rheumatology",
issn = "1462-0324",
publisher = "Oxford University Press",
number = "8",

}

RIS

TY - JOUR

T1 - Development of a new ultrasound scoring system to evaluate glandular inflammation in Sjögren's syndrome

T2 - an OMERACT reliability exercise

AU - Hočevar, Alojzija

AU - Bruyn, George A.

AU - Terslev, Lene

AU - De Agustin, Juan Jose

AU - MacCarter, Daryl

AU - Chrysidis, Stavros

AU - Collado, Paz

AU - Dejaco, Christian

AU - Fana, Viktoria

AU - Filippou, Georgios

AU - Finzel, Stephanie

AU - Gandjbakhch, Frederique

AU - Hanova, Petra

AU - Hammenfors, Daniel

AU - Hernandez-Diaz, Cristina

AU - Iagnocco, Annamaria

AU - Mortada, Mohamed Atia

AU - Inanc, Nevsun

AU - Naredo, Esperanza

AU - Ohrndorf, Sarah

AU - Perko, Nejc

AU - Schmidt, Wolfgang A.

AU - Tamborrini, Giorgio

AU - Tomšič, Matija

AU - Chary-Valckenaere, Isabelle

AU - Zabotti, Alen

AU - Keen, Helen I.

AU - Pineda, Carlos

AU - D'Agostino, Maria Antonietta

AU - Jousse-Joulin, Sandrine

N1 - Publisher Copyright: © The Author(s) 2021. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

PY - 2022

Y1 - 2022

N2 - OBJECTIVE: The aim of this exercise from the OMERACT Ultrasound subgroup on Sjögren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjögren's syndrome (pSS). METHODS: Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. RESULTS: The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. CONCLUSION: The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.

AB - OBJECTIVE: The aim of this exercise from the OMERACT Ultrasound subgroup on Sjögren's syndrome was to develop and assess the reliability of a consensus-based semiquantitative colour Doppler US scoring system for pathologic salivary gland vascularization in patients with primary Sjögren's syndrome (pSS). METHODS: Using the Delphi method, a colour Doppler semiquantitative scoring system for vascularization of bilateral parotid and submandibular glands was developed and tested in static images and on patients (9 pSS patients and 9 sonographers). Intra-reader and inter-reader reliability of grading the salivary glands were computed by weighted Cohen and Light's kappa analysis, respectively. RESULTS: The consensus-based semiquantitative score was: grade 0, no visible vascular signals; grade 1, focal, dispersed vascular signals; grade 2, diffuse vascular signals detected in <50% of the gland; grade 3, diffuse vascular signals in >50% of the gland. In static images, the intra- and inter-reader reliability showed excellent kappa values (95% CI) of 0.90 (0.87, 0.93) and 0.80 (0.74, 0.84), respectively, for all four salivary glands together. In patients, the intra- and inter-reader reliability for all four salivary glands together was kappa = 0.84 (0.73, 0.92) and 0.70 (0.64, 0.76), respectively. CONCLUSION: The consensus-based colour Doppler US scoring for the evaluation of salivary gland vascularization in pSS showed a good inter-reader reliability and excellent intra-reader reliability in static images and in patients. The clinical application of the developed scoring system should be tested in clinical settings.

KW - colour Doppler ultrasound

KW - primary Sjögren’s syndrome

KW - salivary gland vascularization

KW - scoring system

U2 - 10.1093/rheumatology/keab876

DO - 10.1093/rheumatology/keab876

M3 - Journal article

C2 - 34849616

AN - SCOPUS:85135596590

VL - 61

SP - 3341

EP - 3350

JO - Rheumatology

JF - Rheumatology

SN - 1462-0324

IS - 8

ER -

ID: 329284512